Генина

Элина

Алексеевна

Professor

Education:

Саратовский государственный университет имени Н.Г. Чернышевского, физический факультет, радиофизика и электроника, 1993 г., Радиофизика и электроника

Саратовский государственный университет имени Н.Г. Чернышевского, физический факультет, кафедра оптики СГУ, 2001 г.

Thesis and academic degrees:

PhD in Physics and Mathematics (03.00.02 - биофизика), 2002 г.

Terminal degree in Physics and Mathematics (03.01.02 – Биофизика), Управление оптическими свойствами биологических тканей, 2017 г.

Research Interests:

Биологическая и медицинская физика

Биофотоника

Оптика биотканей

Спектроскопия и визуализация в биомедицине

Фототерапия и фототермолиз

Общий стаж:

33 года

Стаж по специальности:

32 года

Work experience:

Engineer, Отдел технической химии и катализа НИИ Химии СГУ, 1993 to 1997

Research fellow, НИЧ СГУ, 1997 to 2001

Assistant, Кафедра оптики СГУ, 2002 to 2003

Senior engineer, Кафедра оптики СГУ, 2000 to 2013

Associate Professor , Кафедра оптики СГУ, 2013 to 2019

Professor

, с 2019 по н.в.

Honors and Awards:

Премия Международной академической издательской компании «Наука» за лучшую публикацию в издаваемых ею журналах, 2011 г.

Награда за лучшую публикацию в журнале Nano Research, 2016 г.

Преподаваемые дисциплины:

Прикладные методы статистики в биологии и медицине

Биометрия

Основы фотобиологии и фотомедицины

Методы фототермической и фотодинамической терапии

Управление оптическими свойствами биотканей

Main Publications:

Главы в монографиях:

Bashkatov A.N., Genina E.A., Tuchin V.V. Optical immersion as a tool for tissue scattering properties control / In: Perspectives in Engineering Optics, Eds. K. Singh and V.K. Rastogi, Anita Publications, B-28 II Floor, Sarvodaya Enclave, New Delhi, India, 2002, pp. 313-334.
Bashkatov A.N., Genina E.A., Tuchin V.V. Measurement of glucose diffusion coefficients in human tissues / Chapter 19 in: Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues, Valery V. Tuchin (editor), Taylor & Francis Group LLC, CRC Press, 2009, pp. 587-621. ‑ ISBN 978-1-58488-974-8.
Genina E.A., Bashkatov A.N., Tuchin V.V. Glucose-induced optical clearing effects in tissues and blood / Chapter 21 in: Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues, Valery V. Tuchin (editor), Taylor & Francis Group LLC, CRC Press, 2009, pp. 657-692. ‑ ISBN 978-1-58488-974-8.
Genina E.A., Bashkatov A.N., Larin K.V., Tuchin V.V. Light-tissue interaction at optical clearing / Chapter 7 in: Laser Imaging and Manipulation in Cell Biology, Francesco S. Pavone (editor), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2010, pp. 115-164 (ISBN: 978-527-40929-7)
Bashkatov A.N., Genina E.A., Tuchin V.V. Tissue Optical Properties / Chapter 5 in: Handbook of Biomedical Optics, David A. Boas (editor), Taylor & Francis Group LLC, CRC Press, 2011, pp. 67-102. – ISBN: 978-1-4200-9036-9.
Genina E.A., Larin K.V., Bashkatov A.N., Tuchin V.V. Glucose and other metabolites sensing in skin / Chapter 12.1.5 in: Handbook of Biophotonics, vol. 2: Photonics for Health Care, Eds. J. Popp, V. Tuchin, A. Chiou, and S.H. Heinemann, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2011, pp. 835-854. ‑ ISBN: 978-3-527-41048-4.
Meglinski I., Doronin A., Bashkatov A.N., Genina E.A., Tuchin V.V. Dermal component-based optical modeling of skin translucency: impact on skin color / Chapter 2 in: Computational Biophysics of the Skin, Bernard Querleux (editor), Pan Stanford Publishing Pte. Ltd., 2014, pp. 25-62 (Print ISBN: 978-9-8144-6384-3; eBook ISBN: 978-9-8144-63850)
Genina E.A., Bashkatov A.N., Sinichkin Yu.P., Yanina I.Yu., Tuchin V.V. Optical Clearing of Tissues: Benefits for Biology, Medical Diagnostics and Phototherapy / Chapter 10 in: Handbook on Optical Biomedical Diagnostics, Vol. 2: Methods, 2nd ed., Valery V. Tuchin (editor), Bellingham, Washington: SPIE Press, 2016, pp. 565-937. (ISBN 9781628419139)
Bucharskaya A.B., Maslyakova G.N., Terentyuk G.S., Navolokin N.A., Bashkatov A.N., Genina E.A., Khlebtsov B.N., Khlebtsov N.G., Tuchin V.V. Gold Nanoparticle-Based Technologies in Photothermal/Photodynamic Treatment: The Challenges and Prospects / Chapter 5 in: Nanotechnology and Biosensors, Edited by Dimitrios P. Nikolelis Georgia-Paraskevi Nikoleli, Elsevier Inc., Amsterdam, 2018, pp. 151-173 (ISBN: 978-0-12-813855-7)
Bashkatov A.N., Zakharov V.P., Bucharskaya A.B., Borisova E.G., Khristoforova Yu.A., Genina E.A., and Tuchin V.V. Malignant Tissue Optical Properties / Chapter 1 in: Multimodal Optical Diagnostics of Cancer, Edited by Valery V. Tuchin, Jürgen Popp, and Valery Zakharov, Springer Nature, Cham, Switzerland, 2020, pp. 3-106 (ISBN 978-3-030-44593-5, ISBN 978-3-030-44594-2 (eBook), https://doi.org/10.1007/978-3-030-44594-2)
Genina E.A., Oliveira L.M.C., Bashkatov A.N., and Tuchin V.V. Optical Clearing of Biological Tissues: Prospects of Application for Multimodal Malignancy Diagnostics / Chapter 3 in: Multimodal Optical Diagnostics of Cancer, Edited by Valery V. Tuchin, Jürgen Popp, and Valery Zakharov, Springer Nature, Cham, Switzerland, 2020, pp. 107-132 (ISBN 978-3-030-44593-5, ISBN 978-3-030-44594-2 (eBook), https://doi.org/10.1007/978-3-030-44594-2)
Yu T., Zhu D., Oliveira L., Genina E.A., Bashkatov A.N., and Тuchin V.V. Tissue optical clearing mechanisms/ Ch. 1 in Handbook of tissue optical clearing: new prospects in optical imaging / edited by Valery Tuchin, Zhu Dan and Elina A. Genina, Boca Raton: CRC Press, 2022, pp. 3-30. DOI: 10.1201/9781003025252-2
Genina E.A., Genin V.D., Zhu J., Bashkatov A.N., Zhu D., and Tuchin V.V. Traditional and innovative optical clearing agents/ Ch. 3 in Handbook of tissue optical clearing: new prospects in optical imaging / edited by Valery Tuchin, Zhu Dan and Elina A. Genina, Boca Raton: CRC Press, 2022, pp. 67-92. DOI: 10.1201/9781003025252-4
Blondel W., Amouroux M., Zaytsev S.M., GeninaE.A., Colas V., Daul Ch., Pravdin A.B., and Tuchin V.V. Human skin autofluorescence and optical clearing / Ch. 5 in Handbook of tissue optical clearing: new prospects in optical imaging / edited by Valery Tuchin, Zhu Dan and Elina A. Genina, Boca Raton: CRC Press, 2022, pp. 109-126. DOI: 10.1201/9781003025252-6
Genina E.A., Bashkatov A.N., Zharov V.P., and Tuchin V.V. In vivo skin optical clearing in humans / Ch. 19 in Handbook of tissue optical clearing: new prospects in optical imaging / edited by Valery Tuchin, Zhu Dan and Elina A. Genina, Boca Raton: CRC Press, 2022, pp. 369-382. DOI: 10.1201/9781003025252-22
Zhernovaya O.S., Genina E.A., Tuchin V.V., and Bashkatov A.N. Optical clearing of blood and tissues using blood components / Ch. 20 in Handbook of tissue optical clearing: new prospects in optical imaging / edited by Valery Tuchin, Zhu Dan and Elina A. Genina, Boca Raton: CRC Press, 2022, pp. 487-516. DOI: 10.1201/9781003025252-23
Yanina I.Yu., Tanikawa Y., Tuchina D.K., Dyachenko (Timoshina) P.A., Iga Ya., Takimoto Sh., Genina E.A., Bashkatov A.N., Terentyuk G.S., Navolokin N.A., Bucharskaya A.B., Maslyakova G.N., and Tuchin V.V. Optical clearing of adipose tissue / Ch. 27 in Handbook of tissue optical clearing: new prospects in optical imaging / edited by Valery Tuchin, Zhu Dan and Elina A. Genina, Boca Raton: CRC Press, 2022, pp. 383-392. DOI: 10.1201/9781003025252-31

Статьи в журналах:

Volkova E.K., Yanina I.Yu., Genina E.A., Bashkatov A.N., Konyukhova J.G., Popov A.P., Speranskaya E.S., Bucharskaya A.B., Navolokin N.A., Goryacheva I.Yu., Kochubey V.I., Sukhorukov G.B., Meglinski I.V., and Tuchin V.V. Delivery and reveal of localization of upconversion luminescent microparticles and quantum dots in the skin in vivo by fractional laser microablation, multimodal imaging, and optical clearing // Journal of Biomedical Optics, Vol. 23(2), 026001-1 ‑ 026001-11, 2018 (doi: 10.1117/1.JBO.23.2.026001) (Q1)
Sdobnov A.Yu., Darvin M.E., Genina E.A., Bashkatov A.N., Lademann J., Tuchin V.V. Recent progress in tissue optical clearing for spectroscopic application // Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Vol. 197, P. 216–229 (2018). (https://doi.org/10.1016/j.saa.2018.01.085) (Q1)
Bashkatov A.N., Berezin K.V., Dvoretskiy K.N., Chernavina M.L., Genina E.A., Genin V.D., Kochubey V.I., Lazareva E.N., Pravdin A.B., Shvachkina M.E., Timoshina P.A., Tuchina D.K., Yakovlev D.D., Yakovlev D.A., Yanina I.Yu., Zhernovaya O.S., Tuchin V.V Measurement of tissue optical properties in the context of tissue optical clearing // Journal of Biomedical Optics, 23(9), 091416-1 – 091416-31, 2018. (DOI: 10.1117/1 .JBO.23.9.091416) (Q1)
Masoumi Sh., Ansari M.A., Mohajerani E., Genina E.A., Tuchin V.V. Combination of analytical and experimental optical clearing of rodent specimen for detecting beta-carotene: phantom study // Journal of Biomedical Optics, Vol. 23, Iss. 9, 095002, 2018 doi: 10.1117/1.JBO.23.9.095002. (Q1)
Bucharskaya A.B., Maslyakova G.N., Chekhonatskaya M.L., Terentyuk G.S., Navolokin N.A., Khlebtsov B.N., Khlebtsov N.G., Bashkatov A.N., Genina E.A., Tuchin V.V. Plasmonic photothermal therapy: approaches to advanced strategy // Lasers in Surgery and Medicine, Vol. 50, Iss. 10, P. 1025-1033, 2018. (DOI 10.1002/lsm.23001) (2.726) (Q1)
Tuchina D.K., Timoshina P.A., Tuchin V.V., Bashkatov A.N., Genina E.A. "Kinetics of rat skin optical clearing at topical application of 40%-glucose: ex vivo and in vivo studies" // IEEE Journal of Selected Topics in Quantum Electronics, Vol. 25, Iss. 1, 7200508, 2019, DOI 10.1109/JSTQE.2018.2830500. (IF = 4.544) (Q1)
Lengert E., Verkhovskii R., Yurasov N., Genina E., Svenskaya Y., Mesoporous carriers for transdermal delivery of antifungal drug // Materials Letters, Vol. 248, 211–213, 2019, doi: https://doi.org/10.1016/j.matlet.2019.04.028 (IF: 2.687) (SJR: 0.782) (Q1)
Rakotomanga P., Soussen Ch., Khairallah G., Amouroux M., Zaytsev S., Genina E., Chen H., Delconte A., Daul Ch., Tuchin V., and Blondel W. Source separation approach for the analysis of spatially resolved multiply excited autofluorescence spectra during optical clearing of ex vivo skin // Biomedical Optics Express, Vol. 10, No. 7, P. 3410-3424, 2019 (https://doi.org/10.1364/BOE.10.003410), (IF: 3.482) (Q1)
Svenskaya Y.I., Genina E.A., Parakhonskiy B.V., Talnikova E.E., Terentyuk G.S., Gorin D.A., Utz S.R., Tuchin V.V., Sukhorukov G.B. A simple non-invasive approach towards efficient transdermal drug delivery based on biodegradable particulate system // ACS Applied Materials & Interfaces, Vol. 11(19), P. 17270-17282, 2019. DOI: 10.1021/acsami.9b04305 (IF: 8.097) (SJR: 2.524) (Q1)
Genina E.A., Bashkatov A.N., Tuchina D.K., Dyachenko (Timoshina) P.A., Navolokin N., Shirokov A., Khorovodov A., Terskov A., Klimova M., Mamedova A., Blokhina I., Agranovich I., Zinchenko E., Semyachkina-Glushkovskaya O.V., Tuchin V.V. Optical properties of brain tissues at the different stages of glioma development in rats: pilot study // Biomedical Optics Express, Vol. 10, No. 10, P. pp. 5182-5197, 2019. (https://doi.org/10.1364/BOE.10.005182) (IF 3.910) (Q1)
Zaitsev S.V., Svenskaya Y.I., Lengert E.V., Terentyuk G.S., Bashkatov A.N., Tuchin V.V., Genina E.A. Optimized skin optical clearing for optical coherence tomography monitoring of encapsulated drug delivery through the hair follicles // J. Biophotonics, Vol. 13(4), e201960020, 2020. DOI:10.1002/jbio.201960020 (IF 3.768) (Q1)
Genina E.A., Bashkatov A.N., Terentyuk G.S., Tuchin V.V. Integrated effects of fractional laser microablation and sonophoresis on skin immersion optical clearing in vivo // J. Biophotonics, Vol. 13(7), e202000101, 2020; https://doi.org/10.1002/jbio.202000101 (IF 3.768) (Q1)
Genina E.A., Surkov Yu.I., Serebryakova I.A., Bashkatov A.N., Tuchin V.V., Zharov V.P. Rapid ultrasound optical clearing of human light and dark skin // IEEE Transactions on Medical Imaging, Vol. 39, no. 10, p. 3198-3206, October 2020; DOI 10.1109/TMI.2020.2989079 (IF 10.048) (Q1)
Zaytsev S.M., Amouroux M., Khairallah G., Bashkatov A.N., Tuchin V.V., Blondel W., Genina E.A. Impact of optical clearing on ex vivo human skin optical properties characterized by spatially resolved autofluorescence and diffuse reflectance spectroscopy // Journal of Biophotonics, 15 (1), e202100202, 2022 (https://doi.org/10.1002/jbio.202100202) (IF=3.207) (Q1)
Tuchin V.V., Genina E.A., Tuchina E.S., Svetlakova A.V., Svenskaya Yu. I. Optical clearing of tissues: issues of antimicrobial phototherapy and drug delivery // Advanced Drug Delivery Reviews, 180 (1), 114037, 2022; https://doi.org/10.1016/j.addr.2021.114037 (IF = 15.470) (Q1)
Yanina I.Yu., Tanikawa Y., Genina E.A., Dyachenko P.A., Tuchina D.K., Bashkatov A.N., Dolotov L.E., Tarakanchikova Y.V., Terentuk G.S., Navolokin N.A., Bucharskaya A.B., Maslyakova G.N., Iga Y., Takimoto Sh., Tuchin V.V. Immersion optical clearing of adipose tissue in rats: ex vivo and in vivo studies // Journal of Biophotonics, 15(7), e202100393, 2022. DOI: 10.1002/jbio.202100393 (IF=3.207) (Q1)

More

Grants anf scientific projects:

Гранты поддержки молодых ученых REC-006 «Нелинейная динамика и биофизика».
Грант поддержки молодых ученых REC-006/SA-006-00 «Фундаментальные исследования и высшее образование» Американского Фонда Гражданских Исследований и Развития (CRDF)
20-32-90043 Мультимодальное исследование патологических образований кожи in vivo для целей оптической диагностики и терапии (Руководитель)
20-52-56005 Разработка оптических технологий для биомедицинской визуализации, диагностики и лазерной терапии (Руководитель)

Additional information:

Индекс Хирша по версии РИНЦ (elibrary.ru) 36

Соредактор монографии Handbook of tissue optical clearing: new prospects in optical imaging / edited by Valery Tuchin, Zhu Dan and Elina A. Genina, Boca Raton: CRC Press, 2022, 658 p. (ISBN 9780367895099 (hardback) | ISBN 9781032118697 (paperback) | ISBN 9781003025252 (ebook). https://dx.doi.org/10.1201/9781003025252 )

Член редколлегии журналов Journal of Biomedical Photonics & Engineering, Diagnostics, Journal of Innovative Optical Health Sciences, and The Open Biomedical Engineering Journal