Svenskaya
Yulia
I.
Education:
Saratov State University, biophysics, PhD, 2013.
Saratov State University, microelectronics and solid-state electronics, engineer, 2010.
Research field:
Biophysics, Drug Delivery, Theranostics, Materials Science, Nanotechnology for Biomedical Applications.
Experience:
2015 – present: Senior Research Associate, Research and Education Institution for Nanostructures and Biosystems, Saratov State University.
2014 – 2015: Associate Research Scientist, Saratov State University.
2010 – 2014: Engineer, Saratov State University.
In 2018, 2016 and 2015 (1-3-month visits): Visiting Researcher, Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy.
In 2014 (3-month visit): Visiting Academic, School of Engineering and Materials Science, Queen Mary University of London, UK.
2012–2013: Visiting Researcher, BIOtech - Interdepartmental Research Centre for Biomedical Technologies, University of Trento, Italy.
In 2011 (1-month visit): Visiting Researcher, Max Planck Institute of Colloids and Interfaces, Potsdam\Golm, Germany.
Awards and Funding:
2017 – 2020: Russian Science Foundation, Presidential funding program for scientific groups under the supervision of young scientists (№ 17-73-20172) – project lead.
2017 – 2019: Russian Ministry of Education and Science, State assignment to higher educational institutions and scientific organizations in the field of scientific (№16.8144.2017/9.10), individual assignment.
2012 – 2013: Erasmus Mundus Scholarship, University of Trento, Italy (№ EMA 2 MULTIC 11).
2012 – 2013: The Foundation for Assistance to Small Innovative Enterprises in Science and Technology, “U.M.N.I.C.” program (№ 01201265349, № 9928р/14246 from 11.01.2012).
2012 – 2013: Russian Government Scholarship for PhD students.
Participation in joint research projects:
2020 – 2022: Research project “Multifunctional nanoscale and nanostructured systems for analytical chemistry and therapeutics”, supported by Russian Ministry of Education and Science (№ FSRR-2020-0002). Project lead – Prof. Irina Goryacheva.
2019 – 2022: Research project “Magneto-controlled nanoobjects of antiblastoma drugs adressable delivery in vivo” supported by Russian Science Foundation (No. 19-73-10123). Project lead – Dr. Maria Lomova.
2015-2017: Research project “Surface enhanced Raman scattering platform based on inorganic porous particles decorated with plasmonic nanoparticles as a sensor for intracellular investigation” supported by Russian Foundation for Basic Research (№ 15-29-01172). Project lead – Prof. Dmitry Gorin.
2014-2017: Research project “Remotely controlled systems for theranostics” supported by Government of the Russian Federation (No. 14.Z50.31.0004), scientific research projects implemented under the supervision of leading scientists at Russian institutions and Russian institutions of higher education. Project lead – Prof. Gleb Sukhorukov.
2013-2016: Research project Dual-Imaging nano/microsized theranostics against cancer” supported by EU, project DINaMIT - Marie Curie Action "International Research Staff Exchange Scheme" (IRSES-GA-2013-612673).
2013-2014: Research project “Remotely controlled nanostructured materials consisting of biosensors and encapsulated bioactive substances” supported by Russian Foundation for Basic Research (№ 12-03-33088). Project lead – Prof. Dmitry Gorin.
1. Gusliakova O., Verkhovskii R., Abalymov A., Lengert, E., Kozlova A., Atkin V., Nechaeva O., Morrison A., Tuchin V., Svenskaya Y. Transdermal platform for the delivery of the antifungal drug naftifine hydrochloride based on porous vaterite particles // Materials Science and Engineering: C. 2021. Vol. 119, 111428.
2. Lengert E.V., Talnikova E.E., Tuchin V.V., Svenskaya Yu.I. Prospective Nanotechnology-Based Strategies for Enhanced Intra-and Transdermal Delivery of Antifungal Drugs // Skin Pharmacology and Physiology. 2020. Vol. 33, 261–269.
3. Zaytsev S. M., Svenskaya Yu. I., Lengert E. V., Terentyuk G. S., Bashkatov A. N., Tuchin V. V., Genina E. A. Optimized skin optical clearing for optical coherence tomography monitoring of encapsulated drug delivery through the hair follicles // Journal of Biophotonics. 2020. e201960020.
4. Douglas T. E., Keppler J. K., Vandrovcová M., Plencner M., Beranová J., Feuereisen M., Parakhonskiy B. V., Svenskaya Yu. I., Atkin V., Ivanova A., Ricquier P., Balcaen L., Vanhaecke F., Schieber A, Bačáková L., Ricquier P. Enhancement of biomimetic enzymatic mineralization of gellan gum polysaccharide hydrogels by plant-derived gallotannins // International Journal of Molecular Sciences. 2020. Vol. 21(7), 2315.
5. Kozlova A. A., German S. V., Atkin V. S., Zyev V. V., Astle M. A., Bratashov D. N., Svenskaya Y.I., Gorin, D. A. Magnetic Composite Submicron Carriers with Structure-Dependent MRI Contrast // Inorganics. 2020. V. 8(2), 11.
6. Svenskaya Y. I., Talnikova E. E., Parakhonskiy B. V., Tuchin V. V., Sukhorukov G. B., Gorin D. A., Utz S. R. Enhanced Topical Psoralen‐UV‐A Therapy via Targeting to Hair Follicles // British Journal of Dermatology. 2020. Vol. 182, 1479-1481.
7. Svenskaya Y. I., Genina E. A., Parakhonskiy B. V., Lengert E. V., Talnikova E. E., Terentyuk G. S., Utz S. R., Gorin D. A., Tuchin V. V., Sukhorukov G. B. A Simple Non-Invasive Approach toward Efficient Transdermal Drug Delivery Based on Biodegradable Particulate System // ACS Applied Materials & Interfaces. 2019. Vol. 11 (19), 17270–17282.
8. Lengert E., Verkhovskii R., Yurasov N., Genina E., Svenskaya Y. Mesoporous Carriers for Transdermal Delivery of Antifungal Drug // Materials Letters. 2019. Vol. 248, 211–213.
9. Utz S.R., Sukhorukov G.B., Tuchin V.V., Gorin D.A., Genina E.A., Svenskaya Y.I., Talnikova E.E. Targeted photosensitizer delivery: A prospective approach to vitiligo photochemotherapy // Vestnik dermatologii i venerologii. 2019. Vol. 95(1). 21-29. (In Russ.).
10. Yanina I. Yu., Svenskaya Yu. I., Prikhozhdenko E. S., Bratashov D. N., Lomova M. V., Gorin D. A., Sukhorukov G. B., Tuchin V. V. Optical monitoring of adipose tissue destruction under encapsulated lipase action // Journal of biophotonics. 2018. e201800058. doi: 10.1002/jbio.201800058 (IF 4.24)
11. Svenskaya Yu. I., Fattah H., Inozemtseva O. A., Ivanova A. G., Shtykov S. N., Gorin D. A., Parakhonskiy B. V. Key Parameters for Size-and Shape-Controlled Synthesis of Vaterite Particles // Crystal Growth & Design. 2018. Vol. 18 (1), 331–337.
12. Yanina I. Y., Navolokin N. A., Svenskaya Yu. I., Bucharskaya A.B., Maslyakova G. N., Gorin D. A., Sukhorukov G. B., Tuchin V. V. Morphology alterations of skin and subcutaneous fat at NIR laser irradiation combined with delivery of encapsulated indocyanine green //Journal of Biomedical Optics. 2017. Vol. 22 (5), 055008 1-7.
13. Svenskaya Yu. I., Pavlov A. M., Gorin D. A., Gould D. J., Parakhonskiy B. V., Sukhorukov G. B. Photodynamic therapy platform based on localized delivery of photosensitizer by vaterite submicron particles// Colloids and Surfaces B: Biointerfaces. 2016. Vol. 146, 171–179.
14. Genina E. A., Svenskaya Y. I., Yanina I. Y., Dolotov L. E., Navolokin N. A, Bashkatov A. N., Terentyuk G. S., Bucharskaya A. B., Maslyakova G. N., Gorin D. A., Tuchin V. V., Sukhorukov G. B. In vivo optical monitoring of transcutaneous delivery of calcium carbonate microcontainers// Biomedical Optics Express. 2016. Vol. 7(6), 2082-2087.
15. Svenskaya Yu., Fattah H., Zakharevich A., Gorin D., Sukhorukov G., Parakhonskiy B. Ultrasonically assisted fabrication of vaterite submicron-sized carriers// Advanced Powder technology. 2016. Vol. 27(2), 618-624.
16. Svenskaya Yu., Gorin D., Parakhonskiy B., Sukhorukov G. Point-wise laser effect on NIH/3T3 cells impregnated with photosensitizer-loaded porous calcium carbonate microparticles// Proceedings of the 15th IEEE International Conference on Nanotechnology. 2015. 1513-1516.
17. Svenskaya Yu., Parakhonskiy B., Haase A., Atkin V., Lukyanets E., Gorin D., Antolini R. Anticancer drug delivery system based on calcium carbonate particles loaded with a photosensitizers// Biophysical Chemistry. 2013. Vol. 182, 11-15.
18. Svenskaya Yu., Navolokin N., Bucharskaya A., Terentyuk G., Kuz’mina A., Burashnikova M., Maslyakova G., Lukyanets E., Gorin D. Calcium carbonate microparticles containing a photosensitizer photosens: Preparation, ultrasound stimulated dye release, and in vivo application// Nanotechnologies in Russia. 2014. Vol. 9, 398–409.
19. Parakhonskiy B., Svenskaya Yu., Yashchenok A., Fattah H., Inozemtseva O., Tessarolo F., Antolini R., Gorin D. Synthesis of size controlled hydroxyapatite particles using calcium carbonate templates and their application as SERS platform //Colloids and Surfaces B: Biointerfaces. 2014. Vol. 118, 243-248.
20. Kubanova A. A., Utz S. R., Kubanov A. A., Persati M., Svenskaya Yu. Perspectives of practical use of nanoparticles in dermatology// Vestnik dermatologii i venerologii. 2017. Vol. 2, 15-20. (In Rus.)
21. A. V. Sadovoy, D. N. Bratashov, A. M. Yashenok, Yu. I. Svenskaya, G. B. Sukhorukov, D. A. Gorin. Liquid crystal-in-water emulsion stabilized by layer-by-layer adsorption of polyelectrolytes and magnetite nanoparticles // Tech.Phys.Lett. 2010, Vol. 36 (1), 88-94.
Patents:
1. Patent (of invention) No RU2633928C1: “Method of transdermal delivery of biologically active substances”, priority date 24.08.2016.
2. Patent (of invention) No RU2698871C1: “Method of photochemotherapy of vitilgo”, priority date 18.08.2018.
Research field:
Biophysics, Drug Delivery, Theranostics, Materials Science, Nanotechnology for Biomedical Applications.
Research interests:
micro- and nanoparticles for delivery of various bioactive compounds focusing on the carrier synthesis (vaterite carriers, core-shell structures, nanocomposite microcapsules, polyelectrolyte multilayer coatings), drug encapsulation and delivery; targeted delivery of photosensitizers; transdermal delivery of biomolecules for systemic and localized therapy; transdermal drug administration for the treatment of skin disorders and for antifungal therapy; transdermal vaccination.
