Цели МНОЦ «Фотоника»:

Комплексное развитие научных исследований и образовательных программ в области оптических информационных технологий, нано- и биофотоники для решения практических задач Саратовского региона

Интегрирование региональной промышленности и здравоохранения в международное пространство оптических технологий для обеспечения конкурентной способности выпускаемой продукции и предоставляемых медицинских услуг

Миссия МНОЦ «Фотоника»:

Разработка и внедрение в учебный процесс новых образовательных технологий

Повышение качества образования специалистов, магистров и аспирантов в нескольких ведущих направлениях физических и междисциплинарных наук - физике оптических явлений, медицинской физике и биофизике

Обеспечение потребности Саратовской области в специалистах высокого уровня по направлениям:

• Лазерные и оптические биомедицинские технологии
• Нанобиотехнологии
• Оптические биосенсоры
• Оптические информационно-телекоммуникационные системы
• Фотонно-кристаллические световоды и системы на их основе

МНОЦ «Фотоника»:

• Физический факультет СГУ
• Научно-образовательный институт оптики и биофотоники СГУ
• Интегрированная образовательная структура «Научно-образовательный центр по оптике, лазерным измерениям и биофотонике» СГУ и Института проблем точной механики и управления РАН (ИПТМУ РАН)

Партнеры:

Более 20 партнеров в РФ, включая Институт прикладной физики РАН, Институт проблем лазерных и информационных технологий РАН, Международный лазерный центр МГУ, Лазерный центр Санкт-Петербургского государственного университета информационных технологий, механики и оптики

Более 40 зарубежных партнеров, включая университеты США (Арканзас, Хьюстон, Техас, Орегон, Дьюк, Пенсильвания, Центральная Оклахома, Калифорния, Бостон); Райс университет (Канада); Европейские университеты: Оулу (Финляндия), Порто (Португалия), Лимерик и Голуэй (Ирландия), Йена (Германия), Университетская клиника Шаритэ Берлина (Германия), Лотарингия (Франция); Институт электроники Болгарской Академии Наук, Королевский колледж науки и медицины (Лондон), Черновицкий университет (Украина), Хуазхонг научно-технологический университет Ухани и Тянзинь университет (КНР), Квансей-Гакуин университет (Япония), Научно-технологический университет Гонконга, Национальный Янг-Минг университет Тайпея (Тайвань), Национальный университет Сингапура, зарубежные высокотехнологичные компании и инновационные центры (США - Palomar Medical Technologies Inc., Burlington; Dentalphotonics, LLC; Photothera, LLC; Канада - Lumerical Solutions, Vancouver, BC; MJC Optical Technology; Израиль - ELFI-TECH, Park Hamada; Nehora Photonics Ltd.; Olympus, Japan, Samsung, Korea; Франция – Международный российско-французский центр инноваций и трансфера технологий при Правительстве Франции в России).

Достижения:

Последние пять лет сотрудники МНОЦ «Фотоника» проводили исследования в области взаимодействия оптического и терагерцового излучения с биологическими тканями и разрабатывали на этой основе когерентно-оптические и спектральные методы медицинской диагностики и лазерной терапии [1-145]. Ключевую роль в этих исследования играло развитие методов управления оптическими свойствами биологических тканей – главным образом изучалось иммерсионное просветление биологических тканей и суспензий клеток [1-13, 32, 36, 40, 43, 48, 53, 59, 61, 62, 66, 67, 77, 79, 80, 85-87, 90, 92, 97, 101, 102, 105, 106, 108, 110-112,116-118, 126, 127, 131, 132, 136, 137, 139, 144], а также измерение и систематизация оптических параметров тканей [1-16, 56, 58, 74, 75, 78, 81, 96, 115, 129, 130, 139]. В результате этих исследований, которые включали теоретические и экспериментальные – физические и биофизические, а также преклинические и клинические исследования, были установлены связи структурно-морфологических особенностей биологических тканей с их оптическими свойствами, изучена кинетика этих связей при воздействии гиперосмотических агентов на ткань и их влияние на распространяющееся в ткани излучение ближнего УФ, видимого, ближнего ИК и терагерцового спектральных диапазонов.

Были разработаны оптические методы исследования и мониторинга изменений параметров биологических тканей и цельной крови при изменении содержания глюкозы и других метаболитов в крови и тканях организма человека и животных [1-5, 17-21, 29, 32, 33, 35, 40, 59, 61, 79, 85, 115].

Получены новые данные для оптических параметров биотканей и скорости диффузии ряда агентов в тканях, в том числе и в твердых (дентин и эмаль зуба, кости черепа, хрящевой ткани) [9, 59, 62, 66, 105, 108, 110, 139, 144]. Получены интересные результаты по просветлению мышечной и других тканей растворами глюкозы [36, 40, 79, 108, 116, 139] и управлению просветлением жировой ткани при фототепловом и фотодинамическом воздействиях [34, 39, 114, 122]. Изучались механизмы просветления на тканевом и клеточном уровне [48, 49, 53, 86, 108, 110, 118, 139].

Исследовалось влияние кровенаполнения на оптические свойства кожи [10, 16] и скорость микроциркуляции в коже и других тканях, разработаны методики измерений на основе полнопольной спекл-визуализации и соответствующие протоколы исследования для животных и человека [17-21, 72, 91, 97, 107, 111, 145].

Разработаны научно-технические основы бесконтактной терагерцовой диагностики на основе исследования спектральных характеристик кожной и других тканей. Впервые предложено просветлять биоткани в терагерцовом диапазоне при воздействии гиперосмотических агентов [53, 57, 117, 140].

Показана важность подавления рассеяния для расширения диапазона измерений и качества получаемой информации при исследованиях разнообразными линейными и нелинейными методами спектроскопии и микроскопии [6-9, 101, 103, 137]. Многочисленные исследования были проведены по разработке методов доставки лекарственных препаратов, просветляющих агентов и наночастиц через кожу и другие ткани [42, 70, 94, 100, 104, 123, 143].

Проведены исследования модификации оптического, теплового и биологического отклика тканей и суспензий микроорганизмов при их взаимодействии с внедренными наночастицами различных типов, включая нанокомпозиты (например, комплексы наночастица-фотосенсибилизатор) при лазерном воздействии с целью разработки новых терапевтических технологий для лечения рака и воспалительных заболеваний [23, 25, 46, 47, 54, 60, 63, 76, 82, 83, 119, 126, 133, 141].

Проведены успешные разработки в области in vivo цитометрии [28, 43, 49, 125, 128, 136], лазерной оптопорации и трансфекции клеток [63, 69, 109], управляемого открытия биологических барьеров, включая гемато-энцефалический барьер (ГЭБ), и диагностики заболеваний мозга [26, 27, 44, 71, 88, 89, 93, 98, 120, 135], а также биосенсорики [29-31, 142]. Написан ряд обобщающих работ, включая монографии, главы в книгах и аналитические обзоры [1-31, 127-139].

Монографии

1.      Tuchin, V.V. (ed.) Coherent-Domain Optical Methods: Biomedical Diagnostics, Environmental Monitoring and Material Science. V. 1, 2/Second edition. Berlin, Heidelberg, N.Y.: Springer-Verlag, 2013, ISBN: 978-1-4614-5175-4 (Print) 978-1-4614-5176-1, 1330 p.

http://www.springer.com/physics/biophysics+%26+biological+physics/book/9...

2.      R.K. Wang and V.V. Tuchin, eds., Advanced Biophotonics: Tissue Optical Sectioning, CRC Press, Taylor & Francis Group, London, 2013 – 681p. ISBN 9781439895818

3.      V.V. Tuchin, Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnostics, 3rd  ed., PM 254, SPIE Press, Bellingham, WA, 2015– 988 p. ISBN: 9781628415162

4.      V.V. Tuchin (Ed.), Handbook of Optical Biomedical Diagnostics. Light-Tissue Interaction, vol.1, 2nd ed., SPIE Press PM262, Bellingham, WA, USA, 2016 – 864 p.

5.      V.V. Tuchin (Ed.), Handbook of Optical Biomedical Diagnostics. Methods, vol.2, 2nd ed., SPIE Press PM263, Bellingham, WA, USA, 2016 – 688 p.

6.      Ruikang K. Wang and Valery V. Tuchin, Optical Coherence Tomography: Light Scattering and Imaging Enhancement, Chapter 16, Coherent-Domain Optical Methods: Biomedical Diagnostics, Environmental Monitoring and Material Science. V. 2, 2nd edition, ed. by V.V. Tuchin, Berlin, Heidelberg, N.Y.: Springer-Verlag, 2013, pp. 665-742. ISBN: 978-1-4614-5175-4

7.      Dan Zhu, Qingming Luo and Valery V. Tuchin, “Tissue Optical Clearing,” Advanced Biophotonics: Tissue Optical Sectioning, Chapter 17, Wang R.K. and Tuchin V.V. (Eds.), CRC Press, Taylor & Francis Group, London, 2013, pp. 621-672. ISBN 9781439895818

8.      R. K. Wang and V. V. Tuchin, “Optical tissue clearing to enhance imaging performance for OCT,” in Optical Coherence Tomography: Technology and Applications, 2nd ed., W. Drexler, J. G. Fujimoto, Eds., Springer International Publishing Switzerland, Cham, Heidelberg, New York, Dordrecht, London, 2015, pp. 1455–1488. ISBN 978-3-319-06420-8

9.      E.A. Genina, A.N. Bashkatov, Yu.P. Sinichkin, I.Yu. Yanina, and V.V. Tuchin, “Optical clearing of tissues: benefits for biology, medical diagnostics, and phototherapy,” Chapter 10 in Optical Biomedical Diagnostics. Methods, vol. 2, 2nd ed., SPIE Press PM263, Bellingham, WA, USA, 2016, pp. 565-637.

10.  Igor Meglinski, Alexander Doronin, Alexey N. Bashkatov, Elina A. Genina, and Valery V. Tuchin, Dermal component based optical modeling of the skin translucency: impact on the skin color, Chapter 2 // Computational Biophysics of the Skin, B. Querleux (ed.), CRC Press, Taylor & Francis Group, London, 2014, p. 25-61. ISBN 9789814463843

11.  J. Mobley, T. Vo-Dinh, and V.V. Tuchin, Optical Properties of Tissues, Chapter 2, Biomedical Photonics Handbook, Tuan Vo-Dinh (Ed.), Taylor & Francis Group, LLC, Boca Raton, FL, CRC Press Inc., 2015, pp. 23-122. ISBN 9781420085143

12.  V.V. Tuchin, Light-Tissue Interactions, Chapter 3, Biomedical Photonics Handbook, Tuan Vo-Dinh (Ed.), Taylor & Francis Group, LLC, Boca Raton, FL, CRC Press Inc., 2015, pp. 123-168. ISBN 9781420085143

13.  N.G. Khlebtsov, I.L. Maksimova, I.V. Meglinski, L. Wang, and V.V. Tuchin, “Introduction to light scattering by biological objects,” Chapter 1 in Handbook of Optical Biomedical Diagnostics. Light-Tissue Interaction, vol.1, 2nd ed., SPIE Press PM262, Bellingham, WA, USA, 2016, pp. 3 -159.

14.  A. B. Pravdin, G. Filippidis, G. Zacharakis, T. G. Papazoglou, V. V. Tuchin. “Tissue phantoms,” Chapter 5 in Handbook of Optical Biomedical Diagnostics. Light-Tissue Interaction, vol.1, 2nd ed., SPIE Press PM262, Bellingham, WA, USA, 2016, pp. 335 - 395.

15.  H. Wabnitz, J. Rodriguez, I. Yaroslavsky,  A. Yaroslavsky, H. Battarbee, and V.V. Tuchin, “Time-resolved imaging in diffusive media,” Chapter 6 in Handbook of Optical Biomedical Diagnostics. Light-Tissue Interaction, vol.1, 2nd ed., SPIE Press PM262, Bellingham, WA, USA, 2016, pp. 401 - 475.

16.  Yu.P. Sinichkin, N. Kollias, G. Zonios, S.R. Utz, and V.V. Tuchin,  “Reflectance and fluorescence spectroscopy of the human skin in vivo,” Chapter 3 in Optical Biomedical Diagnostics. Methods, vol. 2, 2nd ed., SPIE Press PM263, Bellingham, WA, USA, 2016, pp. 99-190.

17.  Qingming Luo, Chao Jiang, Pengcheng Li, Haiying Cheng, Zhen Wang, Zheng Wang, and Valery V. Tuchin Laser Speckle Imaging of Cerebral Blood Flow, Chapter 5, Coherent-Domain Optical Methods: Biomedical Diagnostics, Environmental Monitoring and Material Science. V. 1, 2nd edition, ed. by V.V. Tuchin, Berlin, Heidelberg, N.Y.: Springer-Verlag, 2013, pp. 167-212. ISBN: 978-1-4614-5175-4

18.  Ivan V. Fedosov and Valery V. Tuchin, Bioflow Measuring: Laser Doppler and Speckle Techniques, Chapter 13, Coherent-Domain Optical Methods: Biomedical Diagnostics, Environmental Monitoring and Material Science. V. 1, 2nd edition, ed. by V.V. Tuchin, Berlin, Heidelberg, N.Y.: Springer-Verlag, 2013, pp. 487-564. ISBN: 978-1-4614-5175-4

19.  I.V. Fedosov, Y. Aizu, V.V. Tuchin, N. Yokoi, I. Nishidate, V. P. Zharov and E. I. Galanzha, “Laser Speckles, Doppler and Imaging Techniques for Blood and Lymph Flow Monitoring,” Chapter 6 in Optical Biomedical Diagnostics. Methods, vol. 2, 2nd ed., SPIE Press PM263, Bellingham, WA, USA, 2016, pp. 309-384.

20.  D.A. Zimnyakov and V.V. Tuchin, Speckle Correlometry, Chapter 19, Biomedical Photonics Handbook, Tuan Vo-Dinh (Ed.), Taylor & Francis Group, LLC, Boca Raton, FL, CRC Press Inc.,  2015, 561-586. ISBN 9781420085143

21.  D.A. Zimnyakov, O.V. Ushakova, J.D. Briers, and V.V. Tuchin, “Speckle technologies for monitoring and imaging of tissues and tissue-like phantoms,” Chapter 8 in Optical Biomedical Diagnostics. Methods, vol. 2, 2nd ed., SPIE Press PM263, Bellingham, WA, USA, 2016, pp. 429-495.

22.  A. Douplik, G. Saiko and I. Schelkanova, and V.V. Tuchin, The response of tissue to laser light, Chapter 3, Lasers for Medical Applications: Diagnostics, Therapy and Surgery, Helena Jelinkova (Ed.), Electronic and Optical Materials Series No. 37, Woodhead Publishing, Ltd., 2013, p. 832. ISBN-13: 9780857092373.pp.47-109.

23.  G.S. Terentyuk, I.L. Maksimova, N.I. Dikht, A.G. Terentyuk, B.N. Khlebtsov, N.G. Khlebtsov, V.V. Tuchin, Cancer laser therapy using gold nanoparticles, Chapter 22, Lasers for Medical Applications: Diagnostics, Therapy and Surgery, Helena Jelinkova (Ed.), Electronic and Optical Materials Series No. 37, Woodhead Publishing, Ltd., 2013, p. 832. ISBN-13: 9780857092373.pp. 659-703.

24.  J.T. Alander,  O.M. Villet, T. Pätilä, I.S. Kaartinen, M. Lehecka, T. Nakaguchi, T. Suzuki, and V. Tuchin, Review of Indocyanine Green Imaging in Surgery, in Fluorescence Imaging for Surgeons: Concepts and Applications, Dip, F.D., Ishizawa, T., Kokudo, N., Rosenthal, R. (eds.), Springer International Publishing Switzerland, Cham, Heidelberg, New York, Dordrecht, London, 2015, pp. 35-53; ISBN: 978-3-319-15677-4 (Print),  978-3-319-15678-1 (Online)

25.  A. B. Bucharskaya, G. N. Maslyakova, G. S. Terentyuk, N. A. Navolokin, A. N. Bashkatov, E. A. Genina, B. N. Khlebtsov, N. G. Khlebtsov, V.V. Tuchin, Gold nanoparticle-based technologies in photothermal/photodynamic treatment: the challenges and prospects, D. P. Nikolelis, G.-P. Nikoleli (Eds.), Nanotechnology and Biosensors, Elsevier Inc. 2018.

26.  O. Semyachkina-Glushkovskaya, E. Borisova, A. Namikin, I. Fedosov, A. Abdurashitov, E. Zhinchenko, A. Gekalyuk, M. Ulanova, V. Rezunbaeva, L. Avramov, D. Zhu, Q. Luo, V. Tuchin, “Hypoxia and Neonatal Haemorrhagic Stroke: Experimental Study of Mechanisms,” Advances in Experimental Medicine and Biology, vol. 923, Oxygen Transport to Tissue XXXVIII, Eds. Q. Luo, L. Z. Li, D. K. Harrison, H. Shi, D. F. Bruley, Springer International Publishing Switzerland, 2016, pp 173-179; ISBN: 978-3-319-38808-3 (Print) 978-3-319-38810-6 (Online). DOI: 10.1007/978-3-319-38810-6_23

27.  T. Myllylä, V. Yu.  Toronov, J. Claassen, V. Kiviniemi, and V. V. Tuchin, “Near-infrared spectroscopy in multimodal brain research,” Chapter 10 in Handbook of Optical Biomedical Diagnostics. Light-Tissue Interaction, vol.1, 2nd ed., SPIE Press PM262, Bellingham, WA, USA, 2016, pp. 687 - 735.

28.  Tuchin V.V. In vivo optical flow cytometry and cell imaging, Proc. of the International School of Physics ‘Enrico Fermi,’ Course 181 – Microscopy Applied to Biophotonics, edited by F. S. Pavone, P.T.C. So and P.M.W. French, Societa Italiana di Fisica, Bologna, 2014. 45p. 978-1-61499-412-1

29.  J.S. Skibina, A.V. Malinin, A.A. Zanishevskaya, and V.V. Tuchin, Photonic Crystal Waveguide Sensing, Chapter 1// Portable Biosensing of Food Toxicants and Environmental Pollutants, Series in Sensors, Dimitrios P. Nikolelis, Theodoros Varzakas, Arzum Erdem, Georgia-Paraskevi Nikoleli (Eds.), CRC Press, 2014, 830 p. pp. 1-32. ISBN 9781466576322

30.  M. Jędrzejewska-Szczerska, K. Karpienko, M. S. Wróbel and V. V. Tuchin, “Sensors for Rapid Detection of Environmental Toxicity in Blood of Poisoned People” in Biosensors for Security and Bioterrorism. Applications, Advanced Sciences and Technologies for Security Applications, D.P. Nikolelis and G.-P. Nikoleli (eds.), Springer International Publishing Switzerland (2016), pp. 413-430. DOI 10.1007/978-3-319-28926-7_19.

31.  M. Jędrzejewska-Szczerska, D. Majchrowicz, M. Hirsch, P. Struk, R. Bogdanowicz, M. Bechelany, V. Tuchin, Nanolayers in fiber optic biosensing, D. P. Nikolelis, G.-P. Nikoleli (Eds.), Nanotechnology and Biosensors, Elsevier Inc. 2018.

Статьи

32.  Olga Zhernovaya, Valery V. Tuchin, and Martin J. Leahy, Blood optical clearing by optical coherence tomography, J. Biomed. Opt. 18(2), 026014-1-8 (2013).

33.  Vilensky M.A., Semyachkina-Glushkovskaya O.V., Alexandrov D.A., Tuchin V.V. Timoshina P.A., Kuleshov V. A, Semyachkin-Glushkovsky I.A. Full field speckle-correlation technique in application to visualization of brain cortex and pancreas microcirculation in animal experiment // J. Innovative Opt. Health Sci. 6 (1), 2013.

34.  Irina Yu. Yanina, Natalia A. Trunina, and Valery V. Tuchin Optical coherence tomography of adipose tissue at photodynamic/photothermal treatment in vitro, J. Innovative Opt. Health Sci. 6 (2) 1350010-1-7(2013).

35.  A. A. Zanishevskaya, A. V. Malinin, V. V. Tuchin, Yu. S. Skibina, I. Yu. Silokhin, Photonic Crystal Waveguide Biosensor, J. Innovative Opt. Health Sci. 6 (2), 1350008-1-6 (2013).

36.  Luís Oliveira, Maria Inês Carvalho, Elisabete Nogueira, and Valery V. Tuchin, Optical measurements of rat muscle samples under treatment with ethylene glycol and glucose, J. Innovative Opt. Health Sci. 6 (2), 1350012-1-15(2013).

37.  Boris N. Khlebtsov, Elena S. Tuchina, Vitaly A. Khanadeev, Elizaveta V. Panfilova, Pavel O. Petrov, Valery V. Tuchin, and Nikolai G. Khlebtsov, Enhanced photoinactivation of Staphylococcus aureus with nanocomposites containing plasmonic particles and hematoporphyrin, J. Biophotonics, 6, No. 4, 338–351 (2013) / DOI 10.1002/jbio.201200079

38.  Semyachkina-Glushkovskaya OV, Lychagov VV, Bibikova OA, Semyachkin-Glushkovskiy IA, Sindeev SS, Zinchenko EM, Kassim MM, Braun HA, Al-Fatle F, Al Hassani L, Tuchin VV. The assessment of pathological changes in cerebral blood flow in hypertensive rats with stress-induced intracranial hemorrhage using Doppler OCT: Particularities of arterial and venous alterations. Photon Lasers Med. 2013, 2(2).

39.  Irina Yu. Yanina, Natalia A. Trunina, and Valery V. Tuchin, Photoinduced cell morphology alterations quantified within adipose tissues by spectral optical coherence tomography, J. Biomed. Opt. 18(11), 111407-1-9, 2013.

40.  Luís Oliveira, Maria Inês Carvalho, Elisabete Nogueira, and Valery V. Tuchin, The characteristic time of glucose diffusion measured for muscle tissue at optical clearing, Laser Phys. 23 2013. V. 23. P. 075606-1-7.

41.  Yang Zhang, Yongjun Chen, Yuan Yu, Xingbo Xue, Valery V. Tuchin, Dan Zhu, Visible and near-infrared spectroscopy for distinguishing malignant tumor tissue from benign tumor and normal breast tissues in vitro, J. Biomed. Opt. 18 (7), 077003-1- (July 09, 2013); doi: 10.1117/1.JBO.18.7.077003.

42.  Elina A. Genina, Alexey N. Bashkatov, Leonid E. Dolotov, Galina N. Maslyakova, Vyacheslav I. Kochubey, Ilya V. Yaroslavsky, Gregory B. Altshuler, and Valery V. Tuchin, Transcutaneous delivery of micro- and nanoparticles with laser microporation, J. Biomed. Opt. 18(11), 111406-1-9, 2013. doi: 10.1117/1.JBO.18.11.111406 Импакт-фактор 2.859.

43.  Yulian A. Menyaev, Dmitry A. Nedosekin, Mustafa Sarimollaoglu, Mazen A. Juratli, Ekaterina I. Galanzha, Valery V. Tuchin, and Vladimir P. Zharov, Skin optical clearing for in vivo photoacoustic flow cytometry// Biomedical Opt. Express Vol. 4, No. 12, 3030-3041, 2013; DOI:10.1364/BOE.4.003030. IF 3.176.

44.  V. Toronov, T. Myllylä, V. Kiviniemi, and V.V. Tuchin, Dynamics of the brain: Mathematical models and non-invasive experimental studies, The European Physical Journal Special Topics, 222 (10), pp 2607-2622, 2013 – IF 1.796

45.  Natalia A. Trunina, Maxim E. Darvin, Krisztian Kordas, Anjana Sarkar, Jyri-Pekka Mikkola, Jürgen Lademann, Martina C. Meinke, Risto Myllylä, Valery V. Tuchin, Alexey P. Popov, Monitoring of TiO2 and ZnO nanoparticle penetration into enamel and dentine of human tooth in vitro and assessment of their photocatalytic ability, IEEE J. Select. Tops. Quant. Electr. 20 (3), UNSP 7300108, 2014; DOI: 10.1109/JSTQE.2013.2276082, Article#: 7300108. Импакт-фактор 4.078.

46.  M. Mohl, A. Dombovari, A.-R. Rautio, E. S. Tuchina, P. O. Petrov, O. A. Bibikova, I. Skovorodkin, A. P. Popov, A. Sarkar, J.-P. Mikkola, A. Valtanen, M. Huuhtanen, S. Vainio, R. L. Keiski, A. Prilepskyi, A. Kukovecz, Z. Konya, V. V. Tuchin, K. Kordas, Gypsum-titania fiber nanocomposites for indoor antimicrobial coatings, Journal of Materials Chemistry B. 2, 1307-1316, 2014, DOI: 10.1039/C3TB21644F. Импакт-фактор 6.101.

47.  Georgy Terentyuk, Elizaveta Panfilova, Vitaly Khanadeev, Daniil Chumakov, Elina Genina, Alexey Bashkatov, Valery Tuchin, Alla Bucharskaya, Galina Maslyakova, Nikolai Khlebtsov, and Boris Khlebtsov, Gold nanorods with hematoporphyrin-loaded silica shell for dual-modality photodynamic and photothermal treatment of tumors in vivo, Nano Research. 7(3), 325–337, 2014, DOI 10.1007/s12274-013-0398-3, Импакт-фактор 7.392.

48.  Genina E.A., Bashkatov A.N., Kolesnikova E.A., Basco M.V., Terentyuk G.S., Tuchin V.V. Optical coherence tomography monitoring of enhanced skin optical clearing in rats in vivo. J. Biomed. Opt. 2014. V. 19. № 2. P. 021109. Импакт-фактор 2.859.

49.  M. Kinnunen, A. Bykov, J. Tuorila, T. Haapalainen, A. Karmenyan, and V. Tuchin, Optical clearing at cellular level, J. Biomed. Opt. 2014. V. 19 (7), 071409 Импакт-фактор 2.859.

50.  Pavlov, Alexey; Semyachkina-Glushkovskaya, Oxana; Yang, Zhang; Bibikova, Olga; Pavlova, Olga; Huang, Qin; Zhu, Dan; Li, Pengcheng; Tuchin, Valery; Luo, Qingming, Multiresolution analysis of pathological changes in cerebral venous dynamics in newborn mice with intracranial hemorrhage: adrenorelated vasorelaxation, Physiological Measurement, Article: PMEA-100173.R1IF- 1.496.

51.  A.N. Pavlov, A.I. Nazimov, O.N. Pavlova, V.V. Lychagov, V.V. Tuchin, O.A. Bibikova, S.S. Sindeev, O.V. Semyachkina-Glushkovskaya, Wavelet-based analysis of cerebrovascular dynamics in newborn rats with intracranial hemorrhages, J. Innov. Opt. Health Sci. 7, 1350055 (2014), DOI: 10.1142/S1793545813500557, IF - 1.110.

52.  Adrián F. Peña, Alexander Doronin, Valery V. Tuchin, and Igor Meglinski, Monitoring of interaction of low-frequency electric field with biological tissues upon optical clearing with optical coherence tomography, J. Biomed. Opt. 19(8), 086002-1-6 (2014), DOI: 10.1117/1.JBO.19.8.086002. IF 2.859

53.  Колесников А.С., Колесникова Е.А., Попов А.П., Назаров М.М., Шкуринов А.П., Тучин В.В. Мониторинг дегидратации мышечной ткани in vitro под действием гиперосмотических агентов в терагерцевом диапазоне, Квантовая электроника, том 44, № 7 (505), с. 633 – 640 (2014), IF - 0.897.

54.  Тучина Е.С., Петров П.О., Козина К.В., Ратто Ф., Центи С., Пини Р., Тучин В.В. Использование меченых антителами золотых наностержней при фототермическом воздействии ИК лазерного излучения на Staphylococcus aureus Квантовая электроника, том 44, № 7 (505), с. 683-688 (2014), IF - 0.897.

55.  Генина Э.А., Башкатов А.Н., Тучин В.В. Исследование диффузии фотодинамического красителя индоцианинового зеленого в коже с помощью спектроскопии обратного рассеяния, Квантовая электроника, том 44, № 7 (505), с. 689 – 695 (2014), IF - 0.897.

56.  Башкатов А.Н., Генина Э.А., Кочубей В.И., Рубцов В.С., Колесникова Е.А., Тучин В.В. Оптические свойства тканей толстой кишки человека в спектральном диапазоне 350 – 2500 нм, Квантовая электроника, том 44, № 8 (506), с. 779-784 (2014), IF - 0.897.

57.  A. S. Kolesnikov, E. A. Kolesnikova, K. N. Kolesnikova, D. K. Tuchina, A. P. Popov, A. A. Skaptsov, M. M. Nazarov, A. P. Shkurinov, A. G. Terentyuk, and V. V. Tuchin, THz Monitoring of the Dehydration of Biological Tissues Affected by Hyperosmotic Agents, Phys. Wave Phenomena 22(3),169–176 (2014). DOI: 10.3103/S1541308X14030029.

58.  M.S. Wróbel, A.P. Popov, A.V. Bykov, M. Kinnunen, M. Jędrzejewska- Szczerska, V.V. Tuchin, Multi-layered tissue head phantoms for noninvasive optical diagnostics // J. Innov. Opt. Health Sci. 8 (3) (2015) 1541005-1-10, DOI: 10.1142/S179354581541005, IF - 1.110.

59.  Daria K. Tuchina, Alexey N. Bashkatov, Elina A. Genina, Valery V. Tuchin, Quantification of glucose and glycerol diffusion in myocardium // J. Innov. Opt. Health Sci. 8 (3) (2015) 1541006-1-10, DOI: 10.1142/S1793545815410060 IF - 1.110

60.  A. B. Bucharskaya, G. N. Maslyakova, G. A. Afanasyeva, G. S. Terentyuk, N. A. Navolokin, O. V. Zlobina, D. S. Chumakov, A. N. Bashkatov, E. A. Genina, N. G. Khlebtsov, B. N. Khlebtsov and V. V. Tuchin, The morpho-functional assessment of plasmonic photothermal therapy effects on transplanted liver tumor // J. Innov. Opt. Health Sci. 8 (3) 1541004-1-8 (2015); DOI: 10.1142/S1793545815410047 IF 1.110.

61.  Tuchina D.K., Shi R., Bashkatov A.N., Genina E.A., Zhu D., Luo Q., Tuchin V.V. Ex vivo optical measurements of glucose diffusion kinetics in native and diabetic mouse skin // Journal of Biophotonics 8(4), 332-346, 2015, DOI: 10.1002/jbio.201400138IF 4.447.

62.  Luís M. Oliveira, M. Inês Carvalho, Elisabete M. Nogueira, Valery V. Tuchin, Diffusion characteristics of ethylene glycol in skeletal muscle, J. Biomed. Opt. 20(5), 051019-1-10 (2015) DOI: 10.1117/1.JBO.20.5.051019. IF 2.859.

63.  A.N. Yakunin, Y.A. Avetisyan, and V.V. Tuchin, "Quantification of laser local hyperthermia induced by gold plasmonic nanoparticles," J. Biomed. Opt., 20(5), 051030 (2015). doi:10.1117/1.JBO.20.5.051030. IF 2.859.

64.  A.A. Zanishevskaya, A.A. Shuvalov, Y.S. Skibina, V.V. Tuchin, Blood typing using microstructured waveguide smart cuvette, J. Biomed. Opt., 20(4), 040503 (2015). doi:10.1117/1.JBO.20.4.040503. IF 2.859.

65.  E. A. Genina, V. A. Titorenko, A. V. Belikov, A. N. Bashkatov, V. V. Tuchin, Adjunctive dental therapy via tooth plaque reduction and gingivitis treatment by blue light-emitting diodes tooth brushing, J. Biomed. Opt. 20(12) 128004, 2015; doi: 10.1117/1.JBO.20.12.12800. IF 2.859.

66.  C.-H. Liu, M. Singh, J. Li, Z. Han, C. Wu, S. Wang, R. Idugboe, R. Raghunathan, E. N. Sobol, V. V. Tuchin, M. D. Twa, and K. V. Larin, "Quantitative Assessment of Hyaline Cartilage Elasticity during Optical Clearing using Optical Coherence Elastography," Modern Technologies in Medicine 7, 44-51 (2015).

67.  R. Shi, M. Chen, V.V. Tuchin, and D. Zhu, Accessing to arteriovenous blood flow dynamics response using combined laser speckle contrast imaging and skin optical clearing, Biomedical Optics Express 6 (6), 1977-1989 (2015); DOI:10.1364/BOE.6.001977. IF 3.648.

68.  A. S. Abdurashitov, V.V. Lychagov, O.A. Sindeeva, O.V. Semyachkina-Glushkovskaya, V.V. Tuchin, Histogram analysis of laser speckle contrast image for cerebral blood flow monitoring, Front. Optoelectron, 8(2), 187-194 (2015); DOI 10.1007/s12200-015-0493-z

69.  O. Bibikova, A. Popov, A. Bykov, A. Prilepskii, M. Kinnunen, K. Kordas, V. Bogatyrev, N. Khlebtsov, S. Vainio, and V. Tuchin "Optical properties of plasmon-resonant bare and silica-coated nanostars used for cell imaging," J. Biomed. Opt., 20(7), 076017 (2015). doi:10.1117/1.JBO.20.7.076017. IF 2.859.

70.  Belikov A.V., Shatilova K.V., Skrypnik A.V., Tuchin V.V. Multi‐beam laser‐induced hydrodynamic shock waves used for delivery of microparticles and liquids in skin // Lasers in Surgery and Medicine. 2015. V. 47, №9. P. 723–736. DOI: https://doi.org/10.1002/lsm.22417, IF 2.619.

71.  Alexey N Pavlov, Arkady S Abdurashitov, Olga N Pavlova, Valery V Tuchin, Olga S Sindeeva, Sergey S Sindeev, Oxana V Semyachkina-Glushkovskaya, Hidden stage of intracranial hemorrhage in newborn rats studied with laser speckle contrast imaging and wavelets, Journal of Innovative Optical Health Sciences 8(5), 1550041(2015).IF 1.110

72.  Dmitry D Postnov, Olga Sosnovtseva, Valery V Tuchin, Improved detectability of microcirculatory dynamics by laser speckle flowmetry, J. Biophotonics 8(10), 790-794 (2015).  DOI: 10.1002/jbio.201500152, IF 4.447.

73.  Oxana Semyachkina-Glushkovskaya, Alexey Pavlov, Jürgen Kurths, Ekaterina Borisova, Alexander Gisbrecht, Olga Sindeeva, Arkady Abdurashitov, Alexander Shirokov, Nikita Navolokin, Ekaterina Zinchenko, Artem Gekalyuk, Maria Ulanova, Dan Zhu, Qingming Luo, Valery Tuchin, Optical monitoring of stress-related changes in the brain tissues and vessels associated with hemorrhagic stroke in newborn rats, Biomed. Opt. Express 6(10), 4088-4097 (2015). IF 3.648.

74.  Maciej S Wróbel, Alexey P Popov, Alexander V Bykov, Matti Kinnunen, Malgorzata Jędrzejewska-Szczerska, Valery V Tuchin, Measurements of fundamental properties of homogeneous tissue phantoms, J. Biomed. Opt., 20(4), 045004 (2015).IF 2.859.

75.  Maciej S Wróbel, Malgorzata Jędrzejewska-Szczerska, Stanislaw Galla, Leszek Piechowski, Miroslaw Sawczak, Alexey P Popov, Alexander V Bykov, Valery V Tuchin, Adam Cenian, Use of optical skin phantoms for preclinical evaluation of laser efficiency for skin lesion therapy, J. Biomed. Opt., 20(8), 085003 (2015). IF 2.859.

76.  Boris Khlebtsov, Elena Tuchina, Valery Tuchin, and Nikolai Khlebtsov, Multifunctional Au nanoclusters for targeted bioimaging and enhanced photodynamic inactivation of Staphylococcus aureus, RSC Advances 5, 61639-61649 (2015).IF-3.84

77.  A. Bykov, T. Hautala, M. Kinnunen, A. Popov, S. Karhula, S. Saarakkala, M. T. Nieminen, V. Tuchin, and I. Meglinski, Imaging of subchondral bone by optical coherence tomography upon optical clearing of articular cartilage, J. Biophoton. 9(3):270-275 (2016), doi: 10.1002/jbio.201500130.IF- 4.447.

78.  Башкатов А.Н., Генина Э.А., Козинцева М.Д., Кочубей В.И., Городков С.Ю., Тучин В.В. Оптические свойства биологических тканей брюшины в спектральном диапазоне 350–2500 нм // Оптика и спектроскопия, Т. 120, № 1, С. 6-14, 2016. IF 0.723.

79.  Генина Э.А., Башкатов А.Н., Козинцева М.Д., Тучин В.В. ОКТ-исследование оптического просветления мышечной ткани in vitro с помощью 40%-ного раствора глюкозы // Оптика и спектроскопия, Т. 120, № 1, С. 27-35, 2016. IF 0.723.

80.  Тучина Д.К., Генин В.Д., Башкатов А.Н., Генина Э.А., Тучин В.В. Оптическое просветление тканей кожи ex vivo под действием полиэтиленгликоля // Оптика и спектроскопия, Т. 120, № 1, С. 36-45, 2016. IF 0.723.

81.  Maciej S. Wróbel, Alexey P. Popov, Alexander V. Bykov, Valery V. Tuchin, and Małgorzata Jędrzejewska-Szczerska, Nanoparticle-free tissue-mimicking phantoms with intrinsic scattering, Biomed. Opt. Express 7(6), 2088-2094 (2016); doi: 10.1364/BOE.7.002088 IF 3.648.

82.  A.B. Bucharskaya, S.S. Pakhomy, O.V. Zlobina, G.N. Maslyakova, O.V. Matveeva, I.O. Bugaeva, N.A. Navolokin, B.N. Khlebtsov, V.A. Bogatyrev, N.G. Khlebtsov, V.V. Tuchin, “Alterations of morphology of lymphoid organs and peripheral blood indicators under the influence of gold nanoparticles in rats,” J. Innov. Opt. Health Sci. 9 (1), 1640004 (2016); DOI: http://dx.doi.org/10.1142/S1793545816400046 IF 1.110.

83.  Bucharskaya, A. B., Maslyakova, G. N., Pakhomy, S. S., Zlobina, O. V., Bugaeva, I. O., Navolokin, N. A., Khlebtsov, B. N., Bogatyrev, V. A., Khlebtsov, N. G. and Tuchin, V. V., “The Morphological Changes in the Internal Organs of Laboratory Animals After Prolonged Oral Administration of Gold Nanoparticles,” J. Innov. Opt. Health Sci.  9 1642004 (2016) IF 1.110.

84.  E. A. Genina, Y. I. Svenskaya, I. Yu. Yanina, L. E. Dolotov, N. A. Navolokin, A. N. Bashkatov, G. S. Terentyuk, A. B. Bucharskaya, G. N. Maslyakova, D. A. Gorin, V. V. Tuchin, and G. B. Sukhorukov, “In vivo optical monitoring of transcutaneous delivery of calcium carbonate microcontainers,” Biomed. Opt. Express 7 (6), 2082-2087 (2016); doi: 10.1364/BOE.7.002082 IF 3.648.

85.  W. Feng, R. Shi, N. Ma, D. K. Tuchina, V. V. Tuchin, D. Zhu, “Skin optical clearing potential of disaccharides,” J. Biomed. Opt. 21(8), 081207 (2016); doi: 10.1117/1.JBO.21.8.081207. IF 2.859.

86.  L. Oliveira, M. I. Carvalho, E. Nogueira, and Valery V. Tuchin, “Optical clearing mechanisms characterization in muscle,” J. Innov. Opt. Health Sci. 9 (5) 1650035 (19 pages) (2016); DOI: 10.1142/S1793545816500358 IF 1.110.

87.  P. Peixoto, L. Oliveira, M. I. Carvalho, E. Nogueira, and V. V. Tuchin, “Software development for estimation of optical clearing agent’s diffusion coefficients in biological tissues,” J. Biomed. Photon. & Eng. 1(4) 255-269 (2016); doi: 10.18287/JBPE-2015-1-4-255

88.  O. Sindeeva, E. Borisova, A. Abdurashitov, E. Zhinchenko, A. Gekalyuk, M. Ulanova, A. E. Sharif, V. Razubaeva, S. Serov, L. Yankovskaya, V. Tuchin, and O. Semyachkina-Glushkovskaya, “The stress-related changes in the cerebral blood flow in newborn rats with intracranial hemorrhage: metabolic and endothelial mechanisms,” J. Biomed. Photon. & Eng.  1(4), 248-254; doi: 10.18287/JBPE-2015-1-4-248

89.  O. V. Semyachkina-Glushkovskaya, J. Kurths,  A.N. Pavlov, E. G. Borisova, A. S. Abdurashitov,  D. Zhu, P. Li, Q. Luo, and V. V. Tuchin, “Silent Vascular Catastrophes in the Brain in Term Newborns: Strategies for Optical Imaging,” IEEE J. Selec. Tops. Quant. Electron.  22(3) 6802514 (2016); DOI: 10.1109/JSTQE.2016.2523982  IF 2.828.

90.  D. Chen, N. Zeng, Y. Wang, H. He, V. V. Tuchin, and H. Ma, “Study of optical clearing in polarization measurements by Monte Carlo simulations with anisotropic tissue-mimicking models,” J. Biomed. Opt. 21(8), 081209 (2016), doi: 10.1117/1.JBO.21.8.081209.IF 2.859.

91.  D. D. Postnov, V. V. Tuchin, and O. Sosnovtseva, “Estimation of vessel diameter and blood flow dynamics from laser speckle images,” Biomed. Opt. Express 7 (7), 2759-2768 (2016); DOI:10.1364/BOE.7.002759. IF 3.648.

92.  H. Yu, P. Lee, Y.Ju Jo, K.R. Lee, V.V. Tuchin, Y. Jeong, Y.K. Park, “Collaborative effects of wavefront shaping and optical clearing agent in optical coherence tomography,” J. Biomed. Opt. 21(12), 121510 (2016), doi: 10.1117/1.JBO.21.12.121510.

93.  О.В. Семячкина-Глушковская, А.С. Абдурашитов, С.С. Синдеев, В.В. Тучин, Лазерная спекл-визуализация «автономии» мозгового кровообращения на уровне макро- и микроциркуляции у крыс, «Квантовая электроника», 46, № 6, 496-501 (2016). IF 0.978

94.  Э.А. Генина, Л.Е. Долотов, А.Н. Башкатов, В.В. Тучин, Фракционная лазерная микроабляция кожи: повышение эффективности чрескожной доставки частиц, «Квантовая электроника», 46, № 6, 502-510 (2016). IF 0.978

95.  М.В. Корченова, Е.С. Тучина, В.Ю. Швайко, А.Г. Гюльханданян, А.А. Закоян, Р.К. Казарян, Г.В. Гюльханданян, Б.М. Джагаров, В.В. Тучин, Фотодинамическое воздействие излучения с длиной волны 405 нм на клетки микроорганизмов при их сенсибилизации металлопорфириновыми соединениями, «Квантовая электроника», 46, № 6, 521-526 (2016). IF 0.978

96.  A. N. Bashkatov, E. A. Genina, V.I. Kochubey, and V. V. Tuchin, Quantification of tissue optical properties: perspectives for precise optical diagnostics, phototherapy and laser surgery, J. Phys. D: Appl. Phys. 49 (2016) 501001 (3p); doi:10.1088/0022-3727/49/50/501001, IF 2.772

97.  Alexandrov D.A., Timoshina P.A., Tuchin V.V., Maslyakova G.N., Palatova T.V., Sedov D.S., Izmailov R.R. , “Dynamics of laser speckle imaging of blood flow in the tissues at partial temporary pancreatic ischemia of hungry, fed and alcoholized rats,” Saratov Journal of Medical Scientific Research,12 (2), 106-109 (2016).

98.  Semyachkina-Glushkovskaya O, Borisova E, Abakumov M, Gorin D, Avramov L, Fedosov I, Namykin A, Abdurashitov A, Serov A, Pavlov A, Zinchenko E, Lychagov V, Navolokin N, Shirokov A, Maslyakova G, Zhu D, Luo Q, Chekhonin V, Tuchin V and Kurths J “The Stress and Vascular Catastrophes in Newborn Rats: Mechanisms Preceding and Accompanying the Brain Hemorrhages.” Front. Physiol. 7, 210-1-11(2016). doi: 10.3389/fphys.2016.00210, IF 4.031

99.  A. B. Bucharskaya, G. N. Maslyakova, N. I. Dikht, N. A. Navolokin, G. S. Terentyuk, A. N. Bashkatov, E. A. Genina, V. V. Tuchin, B. N. Khlebtsov, N. G. Khlebtsov,  “Cancer Cell Damage at Laser-Induced Plasmon-Resonant Photothermal Treatment of Transplanted Liver Tumor,” BioNanoSci. 7 (1), 216-221 (2017). DOI:10.1007/s12668-016-0320-z, IF 1.52

100.     Voronin, Denis; Sindeeva, Olga; Kurochkin, Maxim; Mayorova, Oksana; Fedosov, Ivan; Semyachkina-Glushkovskaya, Oksana; Gorin, Dmitry; Tuchin, Valery; Sukhorukov, Gleb, "In vitro and in vivo visualization and trapping of fluorescent magnetic microcapsules in a blood stream", ACS Applied Materials & Interfaces 9 (8), 6885–6893 (2017); Manuscript ID: am-2016-15811d.R1; DOI: 10.1021/acsami.6b15811; http://pubs.acs.org, IF 7.145

101.     A. Sdobnov, M.E. Darvin, J. Lademann and V. Tuchin, A comparative study of ex vivo skin optical clearing using two-photon microscopy, J. Biophoton. 10(9),1115-1123, 2017, DOI: 10.1002/jbio.201600066, IF 4.328.

102.     Э.А. Генина, Н.С. Ксенофонтова, А.Н. Башкатов, Г.С. Терентюк, В.В. Тучин, "Исследование влияния абляции эпидермиса на эффективность оптического просветления кожи in vivo", Квант. электроника, 2017, 47 (6), 561–566.

103.     A. Yu. Sdobnov, V. V. Tuchin, J. Lademann and M. E. Darvin, Confocal Raman microscopy supported by optical clearing treatment of the skin—influence on collagen hydration, J. Phys. D: Appl. Phys. 50 (2017) 285401 (9pp) https://doi.org/10.1088/1361-6463/aa77c9 IF 2.588

104.     Irina Yu. Yanina, Nikita A. Navolokin, Yulia I. Svenskaya, Alla B. Bucharskaya, Galina N. Maslyakova, Dmitry A. Gorin, Gleb B. Sukhorukov, Valery V. Tuchin, “Morphology alterations of skin and subcutaneous fat at NIR laser irradiation combined with delivery of encapsulated indocyanine green,” J. Biomed. Opt. 22(5), 055008 (2017),  doi: 10.1117/1.JBO.22.5.055008. IF 2.530

105.     Alexandrovskaya, Y., Sadovnikov, K., Sharov, A., Sherstneva, A., Evtushenko, E., Omelchenko, A., Obrezkova, M., Tuchin, V., Lunin, V. and Sobol, E., Controlling the near infrared transparency of costal cartilage by impregnation with clearing agents and magnetite nanoparticles. J. Biophotonics, e201700105. doi:10.1002/jbio.201700105. IF 4.328

106.     D. Chen, N. Zeng, Y. Wang, H. He, V. V. Tuchin, and H. Ma, “Mueller matrix polarimetry for characterizing microstructural variation of nude mouse skin during tissue optical clearing,” Biomedical Optics Express 8 (8) 3559-3570 (2017). https://doi.org/10.1364/BOE.8.003559. IF 3.648.

107.     A. Abdurashitov, O. Bragina, O. Sindeeva, Sindeev S., O.V. Semyachkina-Glushkovskaya, V.V. Tuchin Off-axis holographic laser speckle contrast imaging of blood vessels in tissues, J. Biomed. Opt. 2017. V.22(9). 091514

108.     Sónia Carvalho, Nuno Gueiral, Elisabete Nogueira, Rui Henrique, Luís Oliveira, Valery V. Tuchin, Glucose diffusion in colorectal mucosa—a comparative study between normal and cancer tissues, J. Biomed. Opt. 2017. V.22(9), 091506; doi: 10.1117/1.JBO.22.12.125002.

109.     Bibikova O., Singh P., Popov A., Akchurin G., Skaptsov A., Skovorodkin I., Khanadeev V., Mikhalevich D., Kinnunen M., Akchurin G., Bogatyrev V., Khlebtsov N., Vainio S.J., Meglinski I., Tuchin V. Shape-dependent interaction of gold nanoparticles with cultured cells at laser exposure, Laser Phys. Lett. 2017. V.14(5). 055901

110.     Tuchina D.K., Bashkatov A.N., Bucharskaya A.B., Genina E.A., Tuchin V.V. Study of glycerol diffusion in skin and myocardium ex vivo under the conditions of developing alloxan-induced diabetes, Journal of Biomedical Photonics & Engineering, 3(2), 020302, 2017

111.     Timoshina P.A., Bucharskaya A.B., Alexandrov D.A., Tuchin V.V. Study of blood microcirculation of pancreas in rats with alloxan diabetes, Journal of Biomedical Photonics & Engineering. 3(2), 020301, 2017.

112.     Isa Carneiro, Sónia Carvalho, Rui Henrique, Luís Oliveira, Valery V. Tuchin, “Simple multimodal optical technique for evaluation of free/bound water and dispersion of human liver tissue,” J. Biomed. Opt. 22(12), 125002 (2017), doi: 10.1117/1.JBO.22.12.125002.

113.     O. Semyachkina-Glushkovskaya, A. Abdurashitov, A. Pavlov, A. Shirokov, N. Navolokin, O. Pavlova, A. Gekalyuk, M. Ulanova, N. Shushunova, A. Bodrova, E. Saranceva, A. Khorovodov, I. Agranovich, V. Fedorova, M. Sagatova, A. E. Shareef, C. Zhang, D. Zhu, and V. Tuchin, “Laser speckle imaging and wavelet analysis of cerebral blood flow associated with the opening of the blood–brain barrier by sound,” Chinese Optics Letters 15 (9), pp. 090002 (2017). IF 1.948

114.     I. Y. Yanina, A. P. Popov, A. V. Bykov, I. V. Meglinski, V. V. Tuchin, “Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry,” J. Biomed. Opt. 23(1), 016003 (2018), doi: 10.1117/1.JBO.23.1.016003.

115.      E. N. Lazareva, V. V. Tuchin, "Measurement of refractive index of hemoglobin in the visible/NIR spectral range," J. Biomed. Opt. 23 (3), 035004 (2018), doi: 10.1117/1.JBO.23.3.035004

116.     K. V. Berezin, K. N. Dvoretski, M. L. Chernavina, A. M. Likhter, V. V. Smirnov, I. T. Shagautdinova, E. M. Antonova, E. Yu. Stepanovich, E. A. Dzhalmuhambetova, V. V. Tuchin, Molecular modeling of immersion optical clearing of biological tissues, J. Molecular Modeling 24, 45-1-8 (2018); https://doi.org/10.1007/s00894-018-3584-0

117.     O. A. Smolyanskaya, I. J. Schelkanova, M. S. Kulya, E. L.Odlyanitskiy, I. S. Goryachev, A. N. Tcypkin, YA. V. Grachev, YA. G. Toropova, and V. V. Tuchin, Glycerol dehydration of native and diabetic animal tissues studied by THz-TDS and NMR methods, Biomed. Opt. Express  9(3) 1198-1215 (2018); https://doi.org/10.1364/BOE.9.001198

118.     Oliveira Luís M., Carvalho MI, Nogueira EM, Tuchin VV. Skeletal muscle dispersion (400-1000 nm) and kinetics at optical clearing. J. Biophotonics. 2018;11:e201700094. https:// doi.org/10.1002/jbio.201700094

119.     Irina N. Dolganova, Nikita V. Chernomyrdin, Polina V. Aleksandrova, Sheykh-Islyam T. Beshplav, Alexander A. Potapov, Igor V. Reshetov, Vladimir N. Kurlov, Valery V. Tuchin, Kirill I. Zaytsev, “Nanoparticle-enabled experimentally trained wavelet-domain denoising method for optical coherence tomography,” J. Biomed. Opt. 23(9), 091406-1-9 (2018), doi: 10.1117/1.JBO.23.9.091406.

120.     Semyachkina-Glushkovskaya O, Chehonin V, Borisova E, et al. Photodynamic opening of the blood-brain barrier and pathways of brain clearing. J. Biophotonics11(8), e201700287 (2018). https://doi.org/10.1002/jbio.201700287

121.     Namykin AA, Shushunova NA, Ulanova MV, Semyachkina-Glushkovskaya OV, Tuchin VV, Fedosov IV. Intravital molecular tagging velocimetry of cerebral blood flow using Evans Blue. J. Biophotonics. 11(8), e201700343 (2018) https://doi.org/10.1002/jbio.201700343

122.     Yanina IY, Svenskaya YI, Prikhozhdenko ES, D. N. Bratashov, M. V. Lomova, D. A. Gorin, G. B. Sukhorukov, V.V. Tuchin, Optical monitoring of adipose tissue destruction under encapsulated lipase action. J. Biophotonics 2018; e201800058. https://doi. org/10.1002/jbio.201800058

123.     Irina V. Vidiasheva,  Anatolii A. Abalymov,  Maxim A. Kurochkin,  Oksana A. Mayorova,  Maria V. Lomova, Sergey V. German,  Dmitry N. Khalenkow,  Mikhail N. Zharkov,  Dmitry A. Gorin,  Andre G. Skirtach,  Valery V. Tuchin and  Gleb B. Sukhorukov, Transfer of cells with uptaken nanocomposite, magnetite-nanoparticle functionalized capsules with electromagnetic tweezers, Biomaterials Science, 2018, DOI: 10.1039 / C8BM00479J IF 4.210

124.     A. Abdurashitov and V. Tuchin, “A robust model of an OCT signal in a spectral domain,” Laser Phys. Lett. 15 (8), 086201 (2018); https://doi.org/10.1088/1612-202X/aac5c7

125.     O. Pavlova, A. Shirokov, A. Fomin, N. Navolokin, A. Terskov, A. Khorovodov, A. Namykin, A. Pavlov, V. Tuchin, and O. Semyachkina-Glushkovskaya, “Optical in vivo and ex vivo imaging of glioma cells migration via the cerebral vessels: Prospective clinical application of the beta2-adrenoreceptors blockade for glioma treatment,” J. Innov. Opt. Health Sciences 11(4) 1850025 (10 pages) (2018); DOI: 10.1142/S1793545818500256

126.     Shadi Masoumi, Mohammad Ali Ansari, Ezeddin Mohajerani, Elina A. Genina, Valery V. Tuchin, “Combination of analytical and experimental optical clearing of rodent specimen for detecting betacarotene: phantom study,” J. Biomed. Opt. 23(9), 095002 (2018), doi: 10.1117/1.JBO.23.9.095002.

Аналитические обзоры

127.     Dan Zhu, Kirill V. Larin, Qingming Luo, and Valery V. Tuchin, Recent progress in tissue optical clearing, Laser Photonics Rev. 7, No. 5, 732–757 (2013) / DOI 10.1002/lpor.201200056 IF 9.313

128.     V.V. Tuchin, In vivo optical flow cytometry and cell imaging, Rivista Del Nuovo Cimento, 37(7), 375-416 (2014). DOI: 10.1393/ncr/i2014-10102-x. IF 3.364

129.     V.V. Tuchin, Tissue Optics and Photonics: Biological Tissue Structures [Review], J. of Biomedical Photonics & Eng., 1(1), 3-21, 2015.

130.     V.V. Tuchin, Tissue Optics and Photonics: Light-Tissue Interaction [Review], J. of Biomedical Photonics & Eng., 1(2), 98-134, 2015.

131.     Genina E.A., Bashkatov A.N., Sinichkin Yu.P., Yanina I.Yu., Tuchin V.V. Optical clearing of biological tissues: prospects of application in medical diagnostics and phototherapy // Journal of Biomedical Photonics & Engineering, Vol. 1(1), P. 22-58, 2015(ISSN (online) 2411-2844)

132.     V. V. Tuchin, “Polarized light interaction with tissues,” J. Biomed. Opt. 21(7), 071114-1-37 (2016); doi: 10.1117/1.JBO.21.7.071114. IF 2.859.

133.     A. Bucharskaya, G. Maslyakova, G. Terentyuk, A. Yakunin, Y. Avetisyan, O. Bibikova, E. Tuchina, B. Khlebtsov, N. Khlebtsov and V. Tuchin, “Towards effective photothermal/ photodynamic treatment using plasmonic gold nanoparticles (Review)”,  Int. J. Mol. Sci. , 17(8), 1295 (2016); doi:10.3390/ijms17081295. IF 3.257. http://www.mdpi.com/1422-0067/17/8/1295

134.     V.V. Tuchin, Tissue Optics and Photonics: Light-Tissue Interaction II [Review], J. of Biomedical Photonics & Eng., 2(3), 030201-1-31, 2016. doi: 10.18287/JBPE16.02.030201

135.     O.V. Semyachkina-Glushkovskaya, S.G. Sokolovski, A. Goltsov, A.S. Gekaluyk, E.I. Saranceva, O.A. Bragina,V.V. Tuchin, E.U. Rafailov, Laser-induced generation of singlet oxygen and its role in the cerebrovascular physiology, Progress in Quantum Electronics, 55, 112-128, 2017; https://doi.org/10.1016/j.pquantelec.2017.05.001, IF 11.000

136.     Sun RW, Tuchin VV, Zharov VP, Galanzha EI, Richter GT. Current status, pitfalls and future directions in the diagnosis and therapy of lymphatic malformation. J. Biophotonics 11(8), e201700124 (2018); https://doi.org/10.1002/jbio.201700124, IF 4.328

137.     A.Yu. Sdobnov, M.E. Darvin, E.A. Genina, A.N. Bashkatov, J. Lademann, V.V. Tuchin, Recent progress in tissue optical clearing for spectroscopic application, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 197, 216–229 (2018). https://doi.org/10.1016/j.saa.2018.01.085, IF 2.536

138.     Daria K. Tuchina and Valery V. Tuchin, Optical and structural properties of biological tissues under diabetes mellitus, Journal of Biomedical Photonics & Engineering 4 (2) 020201-1-22 (2018); DOI: 10.18287/JBPE18.04.020201

139.     Alexey N. Bashkatov, Kirill V. Berezin, Konstantin N. Dvoretskiy, Maria L. Chernavina, Elina A. Genina, Vadim D. Genin, Vyacheslav I. Kochubey, Ekaterina N. Lazareva, Alexander B. Pravdin, Marina E. Shvachkina, Polina A. Timoshina, Daria K. Tuchina, Dmitry D. Yakovlev, Dmitry A. Yakovlev, Irina Yu. Yanina, Olga S. Zhernovaya, Valery V. Tuchin, "Measurement of tissue optical properties in the context of tissue optical clearing," J. Biomed. Opt. 23(9), 091416 (2018), doi: 10.1117/1.JBO.23.9.091416. IF 2.367

Патенты

140. Г.Г.Акчурин, А.Н.Якунин, А.А.Ангелуц, Ю.А.Аветисян, А.П.Попов, Г.Г.Акчурин, Е.А.Колесникова, И.А.Ожередов, А.А.Скапцов, А.П.Шкуринов, А.С.Колесников, А.В.Балакин, Д.К.Тучина, В.А.Макаров, М.М.Стольниц, В.В.Тучин, С.Р.Утц, Е.М.Галкина, К.Н.Колесникова Патент 2013141495 РФ, МПК A61B5, B82B1, G01N21. «Способ получения терагерцовых изображений раковых опухолей и патологий кожи» - Опубл. 20.03.2015. - Бюл. № 8.

141.     Бучарская А. Б., Маслякова Г. Н., Дихт Н. И., Терентюк Г. С., Наволокин Н. А., Башкатов А. Н., Генина Э. А., Хлебцов Б. Н., Хлебцов Н. Г., Тучин В. В. Патент на изобретение РФ № 2614507, «Способ плазмонно-резонансной фототермической терапии опухолей в эксперименте». Приоритет 15 декабря 2015 г. Регистрация 28 марта 2017 г. Срок действия до 15 декабря 2035 г.

142.     Тучина Д.К., Башкатов А.Н., Генина Э.А., Тучин В.В. Биосенсор для неинвазивного оптического мониторинга патологии биологических тканей / Патент на изобретение РФ № 2633494 от 12.10.2017

143.     Свенская Ю.И., Генина Э.А., Гуслякова О.И., Парахонский Б.В., Горин Д.А., Сухоруков Г.Б., Тучин В.В., Зайцев С.М., Башкатов А.Н., Тальникова Е.Е., Бучарская А.Б., Терентюк Г.С., Утц С.Р. Способ трансдермальной доставки биологически активных веществ / Патент на изобретение РФ № 2633928 от 19.10.2017

144.     Таникава Й. (Олимпус, Япония), Ига Я. (Олимпус, Япония), Такимото С. (Олимпус, Япония), Тучин В. В. (СГУ), Генина Э. А. (СГУ), Башкатов А. Н. (СГУ), Янина И. Ю. (СГУ), Тараканчикова Я. В. (СГУ), Терентюк Г. С. (СГМУ), Тимошина П. А. (СГУ), Тучина Д.К.  (СГУ). Способ наблюдения жировой ткани /Патент на изобретение РФ № 2015 122 756 от 10.01.2017.

145.     Способ измерения скорости течения крови, Патент на изобретение РФ RU №2610559 С1 /М.А.Бороздова, И. В. Федосов, В.В. Тучин. – заявка № 2015136644, 28.08.2015; опубл. – 13.02.2017 Бюл. № 5 – 21 с.

Специальные выпуски журналов

1.      Dan Zhu, Valery V. Tuchin, Qingming Luo, Introduction: Special Issue on Advances in Biophotonics and Biomedical Optics — Part I, J. Innovative Opt. Health Sci. 6 (1), 1302001-1-2 (2013).

2.      M. Fedorov and V.V. Tuchin, Medical Use of Lasers and Photonics in Russia I - Diagnostics, Photon. Lasers Med. 2(2), 81-157, 2013.

3.      M. Fedorov and V.V. Tuchin, Medical Use of Lasers and Photonics in Russia II - Therapy, Photon. Lasers Med. 2(3), 161-240, 2013.

4.      А.Н. Башкатов, В.В. Тучин, Биофотоника, Оптика и спектроскопия, Т. 115, №2, 2013.

5.      Kirill V. Larin ; Valery V. Tuchin and Alex Vitkin (Eds.), "Special Section Guest Editorial: Optical Coherence Tomography and Interferometry: Advanced Engineering and Biomedical Applications", J. Biomed. Opt. 19(2) (2014).

6.      Ilko K. Ilev, Stephen A. Boppart, Stefan Andersson-Engels, Beop-Min Kim, Lev Perelman, Valery Tuchin (Eds.), Biophotonics, IEEE J. Selected Topics in Quantum Electronics 20(2), 6800407-7100912 2014.

7.      E.A. Genina, D. Zhu, and V.V. Tuchin, Special Issue on Optical Technologies in Biophysics and Medicine, J. Innovative Opt. Health Sci. 8 (3), 1502002 (2015).

8.      D. Zhu, S. Zeng, V.V. Tuchin (Eds.), Special Issue on Biomedical Photonics, Front. Optoelectron. DOI 10.1007/s12200-015-0525-8, Higher Education Press and Springer-Verlag Berlin Heidelberg, 2015.

9.      A.V. Priezzhev, H. Schneckenburger, V.V. Tuchin (Eds.), Special section on Laser Applications in Life Sciences, J. Biomed. Opt. 20(5), 051001-1, May 2015.

10.  E. A. Genina, A. N. Bashkatov, and V. V. Tuchin (Eds.), “Special Issue: Optical Technologies for Biomedical Applications,” J. Biomed. Photon. & Eng.  1(4), 208 (2016).

11.  T. Novikova, I. Meglinski, J. C. Ramella-Roman, V. V. Tuchin, “Polarized Light for Biomedical Applications,” J. Biomed. Opt. 21(7), 071001 (2016), doi: 10.1117/1.JBO.21.7.071001. IF 2.859.

12.  D. Zhu, B. Choi, E. Genina, V. V. Tuchin, “Tissue and Blood Optical Clearing for Biomedical Applications,” J. Biomed. Opt. 21(8), 081201 (2016), doi: 10.1117/1.JBO.21.8.081201. IF 2.859.

13.  Башкатов А.Н., Генина Э.А., Приезжев А.В., Тучин В.В. Лазерная биофотоника// Квантовая электроника, Т. 46, № 6, С. 487-542, 2016; DOI: 10.1070/QEL00000. IF 0.897.

14.  Башкатов А.Н., Генина Э.А., Тучин В.В. Оптика и спектроскопия в биофизике и медицине // Оптика и спектроскопия, Т. 120, № 1, С. 3-5, 2016

15.  Martin J. Leahy, Tia E. Keyes, Valery V. Tuchin, and Alexander V. Priezzhev, “Advanced Laser Technologies for Biophotonics,” J. Biomed. Opt. 22(9) (2017). IF 2.859.

16.  V. Tuchin, E. Borisova, M. Jędrzejewska-Szczerska, M. J. Leahy, F. S. Pavone, J. Popp, J. Pozo, V. “Special Issue on Biophotonics in Europe,” Frontiers of Optoelectronics10 (2017).

17.  E. I. Galanzha, V. P. Zharov, V. V. Tuchin, “Photonics meets Lymphatics,” J. Biophoton. 10 (2018). IF 3.818.

18.  Mikhail Yu. Kirillin, Kirill V. Larin, Ilya V. Turchin, Valery V. Tuchin, “Topical Problems of Biophotonics: from Optical Bioimaging to Clinical Biophotonics,” J. Biomed. Opt. 23(9) (2018), doi: 10.1117/1.JBO.23.9.091401.

Приглашенные и пленарные доклады

1.      V.V. Tuchin, Fundamentals and advances of tissue optical clearing, IV International Symposium, Topical Problems of Biophotonics – 2013, 21-27 July 2013, Nizhny Novgorod, Russia, Program and Abstracts, ИПФ РАН, Н. Новгород, p. 4 (invited).

2.      Tuchin V.V. Advances in optical clearing, self-clearing and glucose impact on tissueues // BioPIC 2013, Chair: Martin Leahy, National University of Ireland, Galway, Castleknock Hotel & Country Club, Castleknock, Dublin, Ireland, 25-27 March, 2013.

3.      Valery V. Tuchin, Tissue optical clearing: pathology, mechanics, and light impact, 11th International Conference on Photonics and Imaging in Biology and Medicine, May 26-29, 2013, Wuhan, China. Book of Abstracts, p.34 (invited).

4.      Semyachkina-Glushkovskaya OV, Lychagov VV, Bibikova OA, Semyachkin-Glushkovskiy IA, Sindeev SS, Zinchenko EM, Kassim MM, Al-Fatle F, Al Hassani L, Ulanova M., and Tuchin VV. The experimental study of stress-related pathological changes in cerebral venous blood flow in newborn rats assessed by DOCT, 11th International Conference on Photonics and Imaging in Biology and Medicine, May 26-29, 2013, Wuhan, China. Book of Abstracts, p.47 (invited).

5.      A.N. Pavlov, A.I. Nazimov, V.V. Lychagov, O.V. Semyachkina-Glushkovskaya, Bibikova OA, Sindeev SS, and Tuchin VV., Wavelet-based analysis of cerebrovascular dynamics in newborn rats with intracranial hemorrhages, 11th International Conference on Photonics and Imaging in Biology and Medicine, May 26-29, 2013, Wuhan, China. Book of Abstracts, p.48.

6.      V.V. Tuchin, Skin optics, enhanced imaging and drug delivery, International Photodynamic Medicine Forum, Shanghai, China, 1-3 June, 2013 (invited).

7.      V.V. Tuchin, Nanobiophotonics: Skin Protection, Diagnostics and Therapy. 1st International Conference “Biophotonics – Riga 2013,” 26-31 August, Programme, Abstract, Riga, Latvia, 2013. P. 16 (invited) .

8.      V. Tuchin, Advances in tissue and blood optical clearing for laser diagnostics and treatment, The 21th annual International Conference on Advanced Laser Technologies ALT’13 Budva, Montenegro, September 16–20, 2013 (invited).

9.      Elina A. Genina, Alexey N. Bashkatov, Leonid E. Dolotov, Vyacheslav I. Kochubey, Georgy S. Terentyuk, Boris N. Khlebtsov, Nikolai G. Khlebtsov, and Valery V. Tuchin, Enhaced OCT imaging using molecular and nanoparticle delivery, 6th Finnish-Russian Photonics and Laser Symposium PALS’13, 3-5 October 2013 (invited).

10.  Georgy G. Akchurin, Garif G. Akchurin, Alexander N. Yakunin, Yuri A. Avetisyan, Vitaly A. Khanadeev, Boris N. Khlebtsov, Helen Rendall, Kishan Dholakia, Valery V. Tuchin, Features of 3d temperature fields of colloidal solution of composite nanoparticles exposed to a sequence of femtosecond laser pulses and CW resonant radiation, 6th Finnish-Russian Photonics and Laser Symposium PALS’13, 3-5 October 2013 (invited).

11.  Dan Zhu and Valeriy V. Tuchin, Enhanced biosensing based on chemical or mechanical optical clearing, Asia Communications and Photonics Conference, Beijing China, November 12-15, 2013, ISBN: 978-1-55752-989-3, Scattering Techniques (AF4I) (invited).

12.  Valery Tuchin, "Application of photocatalytic, plasmonic, and upcoversing nanoparticles in vitro and in vivo for biomedical imaging and therapy," BioNanoElectronics in iCT, Biomedicine and Development, Nov 5-6, 2013, FinGerDevNet Program, Biocenter Oulu Doctoral program, Infotech Oulu (invited).

13.  Valery V. Tuchin, Tissue optics and innovations in tissue optical clearing, 12th International Conference on Photonics and Imaging in Biology and Medicine, June 14-17, 2014, Wuhan, China (Plenary).

14.  Oxana Semyachkina-Glushkovskaya, Vladislav V. Lychagov, Alexander L. Kalyanov, Olga Bibikova, Sergey Sindeev, Zhang Yang,; Qin Huang, Dan Zhu, Qingming Luo, Valery V. Tuchin, Optical imaging of intracranial hemorrhage in newborns: modern strategies in diagnostics and direction for future research, Biophotonics: Photonic Solutions for Better Health Care, Chairs: J.Popp, V.V. Tuchin, D.L. Matthews, F.S. Pavone, Photonics Europe, 14 - 17 April 2014, paper # [9129-25] (invited).

15.  Valery V. Tuchin,Tissue optics and in vivo optical clearing technologies, The 13th Conference of the International Society of Optics within Life Sciences, 10-12 June 2014, Ningbo, China (invited).

16.  Valery V. Tuchin,Tissue optics and skin optical clearing, Workshop on Biophotonics, June 18-19, 2014, Fujian Normal University, Fuzhou, China (invited).

17.  Valery V. Tuchin,Skin optical clearing, June 20-21, 2014, Med-X Research Institute，School of Biomedical Engineering, Shanghai Jiao Tong University, China (invited).

18.  Valery V. Tuchin, Light propagation in optically cleared tissue and blood, LALS-2014, June 29th to July 2nd in Ulm, Germany (invited).

19.  Valery V. Tuchin,Tissue optical clearing in a wide wavelength range from visible to terahertz, Sino-German Workshop on Biomedical Photonics-2014, July 1-4, 2014, Ulm, Germany (invited).

20.  Valery Tuchin, Noninvasive Optical Glucose Sensing, Corporate Research and Technology (CRT) of Carl Zeiss AG, July 3-4, Jena, Germany, 2014 (invited).

21.  Valery Tuchin, Controlling of tissue properties in THz-range at application of hyperosmotic agents, COST MB1205 Workshop “Optical methods and devices for cancer diagnostics” Riga 25-27 August, 2014(invited).

22.  Valery Tuchin, Diagnostics at Optical Clearing, 8th International Conference „Advanced Optical Materials and Devices”, Riga 25-27 August, 2014, (invited).

23.  V. Tuchin, Tissue imaging and therapeutic effects at laser‐induced nanoparticle luminescence, heating, and ROS‐generation, ALT-14, Cassis, France, 6-10 October, 2014 (invited).

24.  Valeriy Tuchin, Enhanced Sensing in Biophotonics: From Visible to Terahertz Range, ACP, Biophotonics and Optical Sensors. Asia Communications and Photonics Conference (ACP2014), 11-14 November, 2014, Shanghai, China (invited).

25.  O.V. Semyachkina-Glushkovskaya, V. Lichagov, O. A. Bibikova, S. S. Sindeev, E. Zinchenko, A. Gekaluyk, M. V. Ulanova, Z. Yang, Q. Huang, P. Li, D. Zhu, V.V. Tuchin, Q. Luo, Stroke in newborns: important but poor understood problem, new experimental model, priority for optical diagnostics, mechanisms, Neurophotonics, 9 - 10 February 2015, SPIE 9305, SPIE Photonics West The Moscone Center, San Francisco, California, USA, 2015 (invited).

26.  Tuchin, Valery V., "Tissue optical clearing: New prospects in optical imaging and therapy," IEEE International Conference BioPhotonics, Florence, Italy, 20-22 May 2015 (invited).

27.  Valery Tuchin and Yu. Sinichkin, Fundamentals and curriculum for Master course in biophotonics, International Congress on Biophotonics, 18 – 20 May 2015, Florence, Italy (invited).

28.  A. V. Bykov, T. Hautala, M. Kinnunen, A. P. Popov, S. Karhula, S. Saarakkala, M. T. Nieminen, V. V. Tuchin, Optical clearing of articular cartilage: a comparison of clearing agents, European Conferences on Biomedical Optics (ECBO), June 21 – 25, Munich, Germany. Subconference – Novel Biophotonics Techniques and Applications III [9540-11] (invited).

29.  V.V. Tuchin, Blood perfusion and RBC velocity monitoring and control at tissue optical clearing, The 43rd Annual Meeting of the International Society on Oxygen Transport to Tissue “ISOTT-2015», 11-16.07. 2015, Wuhan, China (invited).

30.  V.V. Tuchin, Nano-optical probes for enhanced imaging, sensing and therapy, V International Symposium: Topical Problems of Biophotonics - 2015, 20-24 July, Nizhny Novgorod, Russia, 2015 (invited).

31.  Genina E.A., Bashkatov A.N., Volkova E.V., Yanina I.Yu., Navolokin N.A., Dolotov L.E., Timoshina P.A., Genin V.D., Terentyuk G.S., Svenskaya Yu.I., Bucharskaya A.B., Kochubey V.I., Popov A.P., Gorin D.A., Sukhorukov G.B., Tuchin V.V. Optical monitoring of transcutaneous particle delivery using fractional laser microablation, V International Symposium: Topical Problems of Biophotonics - 2015, 20-24 July, Nizhny Novgorod, Russia, 2015 (invited)

32.  V.V. Tuchin, Intensified laser diagnostics and therapy at tissue optical clearing, 23th Annual International Conference on Advanced Laser Technologies (ALT’15), Faro, Portugal, September 7-11, 2015 (invited).

33.  V.V. Tuchin, FiDiPro Project on Biophotonics: Finland-Russian Collaboration, 7-th Finnish-Russian Photonics and Laser Symposium PALS'15, September 22-25, 2015, Saratov, Russia (invited)

34.  Genina E.A., Bashkatov A.N., Tuchin V.V. Mechanisms of tissue optical immersion clearing // 7-th Finnish-Russian Photonics and Laser Symposium PALS'15, September 22-25, 2015, Saratov, Russia (invited)

35.  A. P. Popov, E. V. Khaydukov, A. V. Bykov, V. A. Semchishen, V. V. Tuchin, I. V. Meglinski, Improvement of upconversion deep-tissue imaging with optical clearing 7-th Finnish-Russian Photonics and Laser Symposium PALS'15, September 22-25, 2015, Saratov, Russia (invited)

36.  A. N. Bashkatov, E. A. Genina, V. V. Tuchin, Optical properties of tissues in the visible– NIR spectral range, 7-th Finnish-Russian Photonics and Laser Symposium PALS'15, September 22-25, 2015, Saratov, Russia (invited).

37.  A. N. Yakunin, Yu. A. Avetisyan, A.A. Bykov, V.V.Tuchin, About influence of nanoparticle size and laser pulse duration on biotissue's damage, Saratov Fall Meeting (SFM’15), International Symposium on Optics and Biophotonics III (Conference on Internet Biophotonics VIII), Saratov, Russia, September 22-25, 2015 (invited).

38.  Yanina I.Yu., Tanikawa Y., Genina E.A., Tarakanchikova Y.V., Timoshina P.A., Tuchina D.K., Bashkatov A.N., Dolotov L.E., Terentyuk G.S., Navolokin N.A., Maslyakova G.N., Iga Y., Takimoto Sh., Tuchin V.V. In vitro and in vivo kinetics of optical clearing of fat tissue in rats // Saratov Fall Meeting (SFM’15), International Symposium on Optics and Biophotonics III (Conference on Internet Biophotonics VIII), Saratov, Russia, September 22-25, 2015 (invited)

39.  V.V. Tuchin, Tissue Optics and Photonics, 3rd FAST-DOT Summer School «Photonics meets Biology», 28 September - 2 October 2015, Royal Mare Thalasso & Spa Hotel, Anissaras, Crete, Greece (invited).

40.  Valery Tuchin, Enhanced optical diagnostics and phototherapy at tissue optical clearing, Micro-Photonics, Preview Event, Berlin Exhibition Grounds: Messe-Berlin, 26-27 November, 2015 (invited).

41.  Valery V. Tuchin, Enhanced Imaging and Sensing in Biophotonics: from UV to Terahertz, The 2nd Israeli Biophotonics Conference (IBPC-2), December 1-2, 2015, Bar-Ilan University, Ramat-Gan, Israel (invited).

42.  Tuchin V.V., World and European Consortia, Platforms and COST Projects on Biophotonics, Workshop, "THz Consortium: International concortium on terahertz photonics and optoelectronics"; Conference "Interdisciplinary Research Projects Organization in the Format of Multilateral Cooperation", December 16-17, 2015, Moscow State University, Russia (invited).

43.  Valery V. Tuchin, “Advances in skin optical clearing (Invited)”, [9689-19] SPIE Photonics West, The Moscone Center, San Francisco, California, USA, 13–18 February 2016.

44.  V. V. Tuchin, “Enhanced Microscopy and Imaging at Optical Clearing: from in Vitro to in Vivo,”  [invited], Focus on Microscopy (FOM2016), Taipei, Taiwan, 20 - 23 March 2016.

45.  O. Semyachkina-Glushkovskaya, A. Pavlova, N. Navolokin, V. Lychagov, A. Abdurashitov, E. Zinchenko, A. Gekaluk, D. Zhu, R. Shi, Q. Luo, and V. Tuchin, “Cerebral venous circulatory disturbance as an informative prognostic marker for neonatal hemorrhagic stroke (invited),” Biophotonics: Photonic Solutions for Better Health Care, SPIE Photonics Europe Symposium, 9887, Brussels, 3 - 7 April 2016.

46.  V. V. Tuchin, “UV to THz Enhanced Tissue Imaging at Immersion Clearing: from in vitro to in vivo” (key-note), 7th International Conference «Nanoparticles, nanostructured coatings and microcontainers: technology, properties, applications», Tomsk, 12-15 May 2016.

47.  V.V. Tuchin, Advances and perspectives for in vivo optical clearing of tissues (invited), Launching Symposium of KI for Health Science and Technology, 2-3 June, Daejeon, Korea.

48.  V.V. Tuchin, “Enhanced optical imaging and laser treatment in medicine: from UV to terahertz,” (Plenary), 4th International Symposium "Lasers in Medicine and Biophotonics", Laser Optics, St. Petersburg, June 27-July 2, 2016.

49.  V.V. Tuchin, “Tissue optical clearing as a novel modality to control laser tissue interaction” (invited),  “Fundamentals of Laser Assisted Micro– and Nanotechnologies” (FLAMN-16) – International Symposium (In frames of International Congress «Lasers & Photonics 2016»), June 27-July 1, 2016.

50.  V.V. Tuchin, “Enhanced optical imaging: from UV to terahertz and from in vitro to in vivo,” OPTO2016 and COST, Gdansk, July 6-9, 2016.

51.  V.V. Tuchin, “Nanoparticle mediated photo-protection and – therapy” (invited), The 7th International Conference on Metamaterials, Photonic Crystals and Plasmonics, META’16 Malaga – Spain, June 25-28, 2016.

52.  V.V. Tuchin, “Advances in Tissue Optics, Laser Medical Imaging and Treatment during Optical Clearing,” 24th International conference on Advanced Laser Technologies, 12-16 September 2016, Galway, Ireland (invited).

53.  V.V. Tuchin, “Tissue and cell optical clearing as a tool for enhanced microscopy and imaging: from in vitro to in vivo,” International Conference on Advanced Fluorescence Imaging Methods, Sochi-Dagomys, Russia, October 3-9, 2016 (plenary) http://www.adflim.org/page58.html

54.  V.V. Tuchin, O. Bibikova, U. Zabarylo, J. Haas, A. Lorente, O. Minet, B. Mizaikoff, V. Artyushenko “Enhanced Medical Optical Imaging Using Multimodality, Optical Clearing and Nanoparticle Labelling,” Micro photonics 2016 International Congress Expo, October 11-13, 2016, Berlin Messe (invited) http://www.micro-photonics.de/media/lob/lob_media/lob_pdf/2016_3/kongres... .

55.  V.V. Tuchin, “Advances and mechanisms of tissue optical clearing,” International Conferences on Laser Applications in Life Sciences (LALS2016), Shenzhen, China October 14-18, 2016 (invited) www.lals2016.org.

56.  V.V. Tuchin, “Creation of new diagnostic/therapeutic windows in tissues: from UV to terahertz,” Asia Communications and Photonics Conference, Nov. 2-5, 2016, Shangri-La Hotel, Wuhan, China (invited).

57.  V.V. Tuchin, “Enhanced spectroscopy and imaging of tissues by immersion clearing: from UV to terahertz,” Japan-Taiwan Medical Spectroscopy International Symposium (JTMSIS), December 4th-7th, 2016, Awaji Island, Japan (plenary).

58.  L. Fu, J. Kurths, Y. Zhang, S. Xu, Z. Li, P. Hu, Yu. P. Sinichkin, V. V. Tuchin, Q. Luo, “Innovative curriculum for Optical Biomedical Engineering in China and Russia,” The 14th International Conference on Education and Training in Optics and Photonics (ETOP-2017), May 29-31, 2017, Zhejiang University, Hangzhou, China (invited).

59.  Valery Tuchin, “Tissue optical clearing: new diagnostic/therapeutic windows,” Workshop on Biomedical Optics, June 6-8, 2017, Center for Research in Medical Imaging (CERIMED), La Timone Hospital in Marseille, Aix-Marseille University and Institut Fresnel, France (invited).

60.  Valery Tuchin, “The benefits of tissue optical clearing for cancer theranostics,” The 3rd International Conference Current Trends in Cancer Theranostics (CTCT-2017), June 25-29, 2017, Pakruojis, Lithuania (key-note).

61.  Valery Tuchin, “Tissue spectroscopy and imaging at optical clearing,” 2nd School Advanced Fluorescence Imaging Methods (ADFLIM), July 26-28, 2017, Sant-Petersburg, Russia.  http://www.adflim.org/Page52.html (invited).

62.  Valery Tuchin, “Enhanced imaging of tissues by immersion clearing/contrasting: from x-ray to terahertz,” IV International Symposium Topical Problems of Biophotonics (TPB-2017), July 26- August 3, 2017, Sant-Petersburg – Nizhny-Novgorod, Russia. http://www.biophotonics.sci-nnov.ru/ (invited).

63.  Valery Tuchin, “Tissue Immersion Clearing for Enhanced Imaging within the Ultra-Broad Wavelength Range: from Free Electrons to Optical and Terahertz Waves,” The 2nd International Conference “Biophotonics - Riga 2017”, August 27–29, 2017, University of Latvia, Riga, Latvia (invited).

64.  Valery Tuchin, “Creation and improvement of tissue optical windows for laser probing and treatment using immersion optical clearing,” The 25th International Conference on Advanced Laser Technologies (ALT’17), September 10-15, 2017, Busan, Korea. http://altconference.org/alt17 (invited).

65.  Valery Tuchin, “Tissue optical clearing as a tool for enhanced imaging and spectroscopy,” “Photonics meets Biology,” Summer School, September 18-22, 2017, Tarragona, Spain (key-note).

66.  Тучин В.В., “Управление оптическими свойствами биологических тканей в широком диапазоне от УФ до миммлиметровых волн: новые окна прозрачности,” XXX Школа-симпозиум по голографии, когерентной оптике и фотонике, 2– 6 октября 2017 г., Балтийский Федеральный Университет им. Иммануила Канта, Калининград. https://www.kantiana.ru/school-symposium/ (invited).

67.  Valery Tuchin, “Tissue Optical Clearing/Contrasting for Image Enhancement in the Ultra-Broad Wavelength Range,” Asia Communications and Photonics Conference (ACP), November 10-13, 2017, Guangzhou, China (invited).

68.  Valery Tuchin,”Enchanced OCT imaging and monitoring of drug delivery,” EPIC Biophotonics Workshop Towards in vivo imaging, 30 Nov. – 1 Dec. 2017, Amsterdam, The Netherlands, p.5, 2017 (key-note)

69.  V.V. Tuchin, E.I. Galanzha, V.P. Zharov, “Optical amplification of in vivo photoacoustic flow cytometry,” TuSMB-01, 5th International A.M. Prokhorov Symposium on Lasers in Medicine and Biophotonics, the  International Conference on Laser Optics ICLO 2018, http://laseroptics.ru/ , St. Petersburg, June 4-8, 2018 (invited).

70.  K.I. Zaytsev, N.V. Chernomyrdin, K.M. Malakhov, Sh.-I.T. Beshplav, S.A. Goryaynov, V.N. Kurlov, I.V. Reshetov, A.A. Potapov,V.V. Tuchin, “In vitro terahertz dielectric spectroscopy of human brain tumors,” WeSMB-25, 5th International A.M. Prokhorov Symposium on Lasers in Medicine and Biophotonics, the  International Conference on Laser Optics ICLO 2018, http://laseroptics.ru/ , St. Petersburg, June 4-8, 2018 (invited).

71.  O.V.Semyachkina-Glushkovskaya, E.U. Rafailov, S.G. Sokolovsky, E.G. Borisova, V. Mantareva, I. Angelov, A. Shirokov, N. Navolokin, N.A. Shushunova, A.P. Khorovodov, A.V. Terskov, A.A. Bodrova, M.V. Ulanova, E. Shrif, V.V. Tuchin, J. Kurths, “Laser technologies of targeted opening of blood-brain barrier for drug brain delivery,” WeSMB-29, 5th International A.M. Prokhorov Symposium on Lasers in Medicine and Biophotonics, the  International Conference on Laser Optics ICLO 2018, http://laseroptics.ru/ , St. Petersburg, June 4-8, 2018 (invited).  

72.  V. N. Kurlov, I.A. Shikunova, G.M. Katyba, K.I. Zaytsev, N.V. Chernomyrdin, I.N. Dolganova, V.V. Tuchin, I.V. Reshetov, “Biomedical applications of sapphire shaped crystals,” WeSMB-31, 5th International A.M. Prokhorov Symposium on Lasers in Medicine and Biophotonics, the  International Conference on Laser Optics ICLO 2018, http://laseroptics.ru/ , St. Petersburg, June 4-8, 2018 (invited).

73.  L. Oliveira, I. Carneiro, S. Carvalho, R. Henrique, D. K. Tuchina, P. A. Timoshina, A. N. Bashkatov, E. A. Genina, V. V. Tuchin, “Tissue optical clearing as a diagnostic tool for tissue pathology differentiation,” WeSMB-37, 5th International A.M. Prokhorov Symposium on Lasers in Medicine and Biophotonics, the  International Conference on Laser Optics ICLO 2018, http://laseroptics.ru/ , St. Petersburg, June 4-8, 2018 (invited).

74.  Valery Tuchin, ”Optical clearing as a promising technique for in vivo optical imaging and treatment of hidden pathologies,” 12th Workshop on Advanced Multiphoton and Fluorescence Lifetime Imaging Techniques FLIM2018” Conference in Berlin-Adlershof, Max-Born-Institute, June 15 - 16, 2018 (invited).

75.  Valery V. Tuchin, “Optical clearing as a promising technology for in vivo laser diagnostics and treatment of hidden pathologies,” Advanced Laser Technologies (ALT’18), September 09-14, 2018, Tarragona, Spain (plenary).

76.  O.Semyachkina-Glushkovskaya, E. Vodovosova, E. Borisova, A. Khorovodov, A. Terskov, I. Agranovich, A. Mamedova, M. Klimova, C. Zhang, W. Feng, Yu. Li, T. Yu, D. Zhu, V. Tuchin, “Photodynamic opening of blood-brain barrier: non-invasive approaches and age differences,” Advanced Laser Technologies (ALT’18), September 09-14, 2018, Tarragona, Spain (invited).

77.  Kirill I. Zaytsev, I.N. Dolganova, N.V. Chernomyrdin, G.A. Komandin, M.A. Schcedrina3, S.-I.T. Beshplav, S.A. Goryaynov, I.V. Reshetov, A.A. Potapov, and V.V. Tuchin, “A potential of optical coherence tomography and terahertz pulsed spectroscopy for intraoperative diagnosis of brain tumors,” Advanced Laser Technologies (ALT’18), September 09-14, 2018, Tarragona, Spain (invited paper).

78.  I. Carneiro, S. Carvalho1, V. Silva, R. Henrique, L. Oliveira, V. V. Tuchin, “Kinetics of optical properties of human colorectal tissues during optical clearing – a comparative study between normal and pathological tissues,” Advanced Laser Technologies (ALT’18), September 09-14, 2018, Tarragona, Spain (invited).

79.  Elina A. Genina, Alexey N. Bashkatov, Daria K. Tuchina, Polina A. Timoshina, Oxana V. Semyachkina-Glushkovskaya, Valery V. Tuchin, “Optical properties of rat brain tissue in the normal state and at the different stages of glioma development,” Advanced Laser Technologies (ALT’18), September 09-14, 2018, Tarragona, Spain (invited).

80.  Valery V. Tuchin "Biophotonics in Russia: main directions and development prospects" X International Conference "Basic Problems of Optics (BPO’18)", St. Petersburg October 15-19, 2018 (plenary).

81.  Valery Tuchin,”Tissue optical clearing as a platform for in vivo optical imaging and treatment of hidden pathologies: from UV to terahertz,” International Conference on Laser Applications in Life Sciences (LALS) in Israel, November 18-20, 2018, Bar-Ilan University, Israel (plenary).

Научные проекты

Разработка компьютерного диагностического комплекса для выявления ранних патологических изменений в кровотоке мозга, 2012 – 2013, ФЦП «Исследования и разработки по приоритетным направлениям развития научно-технического комплекса России на 2007-2013 годы», гос. контракт 11.519.11.2035. В рамках международного договора с Австралией.

Развитие физических основ и приложений высокоразрешающей томографической и поляризационной микроскопии для субмикронного анализа объемной структуры объектов технического и биологического происхождения, 2012 – 2013, ФЦП "Научные и научно-педагогические кадры инновационной России" на 2009 - 2013 годы, гос. контракт 14.B37.21.0728.

Разработка когерентно-оптических биосенсоров на генетическом, клеточном и организменном уровнях организации, 2012 – 2013, ФЦП "Научные и научно-педагогические кадры инновационной России" на 2009 - 2013 годы, гос. контракт 14.B37.21.0563.

Лазерная трансфекция клеток и тканей, меченных золотыми нанооболочками, 2012 – 2013, РФФИ, грант 12-02-92610-КО_а. Руководитель

Biophotonic technologies for novel diagnostic and therapeutic applications, FiDiPro (Finland Distinguished Professor) Program, awarded by TEKES, №40111/1 (2011-2014), V.V. Tuchin – FiDiPro.

Грант РФФИ: 13-02-91176-ГФЕН_а, Механизмы оптического просветления кожи в норме и патологии, количественная оценка, 2013-2014.

Научный проект по организации Международного симпозиума по оптике и биофотонике "Saratov Fall Meeting 2013". Грант РФФИ, 13-02-06107Г_2013. 2013.

Разработка научно-технических основ бесконтактной терагерцовой диагностики распространенных заболеваний человека (включая онкологические и эндокринные) на основе исследования спектральных характеристик кожной ткани и крови, 2013, ФЦП «Исследования и разработки по приоритетным направлениям развития научно-технического комплекса России на 2007-2013 годы», гос. контракт 14.512.11.0022.

«Исследование оптических и биофизических свойств биологических тканей и жидкостей, направленное на создание фундаментальных основ оптической медицинской диагностики и лазерной терапии, включая point-of-care медицину», грант Президента РФ для государственной поддержки ведущих научных школ Российской Федерации НШ-703.2014.2 (2014-2015).

Грант РФФИ: № 14-02-00526а, Разработка чувствительных методов диагностики риска развития интракраниальных геморрагий в первые дни после рождения (2014-2016).

«Дистанционно управляемые наноструктурированные системы для адресной доставки и диагностики», грант Правительства Российской Федерации 14. Z50.31.0004 для государственной поддержки научных исследований, проводимых под руководством ведущих ученых (Г.Б. Сухоруков) в российских образовательных учреждениях высшего профессионального образования, научных учреждениях государственных академий наук и государственных научных центрах Российской Федерации, (2014- 2017).

Грант РНФ: 14-15-00186, Прецизионная метрология пространственно-временных оптических и тепловых процессов, индуцированных импульсным лазерным облучением биологических тканей и клеток, допированных наночастицами (2014-2016).

Грант РНФ: 14-15-00128, Ворота гематоэнцефалического барьера: механизмы регуляции, их зависимость от состояния организма и возраста, способы коррекции с помощью супрамолекулярных транспортных систем (2014-2016).

Научный проект по организации Международного симпозиума по оптике и биофотонике "Saratov Fall Meeting 2014". Грант РФФИ, 14-02-20101г_2014. 2014.

Научный проект по организации Международного симпозиума по оптике и биофотонике "Saratov Fall Meeting 2015". Грант РФФИ,15-02-20633 г_2015. 2015.

Грант Президента РФ для государственной поддержки ведущих научных школ Российской Федерации № 14.Z57.16.7898-НШ «Оптика и биофотоника биологических тканей: методы медицинской диагностики и терапии» (2016-2017).

Грант РФФИ:16-02-20591 г_2016. Научный проект по организации Международного симпозиума по оптике и биофотонике "Saratov Fall Meeting 2016". 2016.

Грант РФФИ: № 16-32-50128 мол_нр, «Влияние наночастиц, используемых для биомедицинских применений, на микрореологические свойства крови», 2016.

Грант РФФИ: №17-02-00358, "Технология "открытия" гематоэнцефалического барьера с помощью лазерной генерации синглетного кислорода," 2017-2019

Государственное задание Министерства образования и науки Российской Федерации: 17.1223.2017/ПЧ, «Разработка технологий оптического «открытия» гематоэнцефалического барьера и персонифицированного лечения агрессивных форм глиальных опухолей», 2017-2019.

Грант РФФИ: № 17-00-00272 «Формирование изображений биологических тканей (биоимиджинга) с помощью использования магнитных наночастиц и гиперосмотических агентов», в рамках комплексного проекта 17-00-00275 (K) «Информативные признаки социально-значимых заболеваний в терагерцовом диапазоне частот: мультиспектральные исследования биологических тканей, жидкостей и выдыхаемого воздуха», 2017-2019.

Грант РФФИ: № 18-52-16025 НЦНИЛ_а «Исследование и разработка эффективных оптических технологий для диагностики в дерматологии», 2018-2020.

НИР «Лазерная фемтосекундная оптопорация клеток и биотканей для трансфекции клеток in situ,» Программа фундаментальных исследований Президиума РАН № 32 «Наноструктуры: физика, химия, биология, основы технологий» подпрограмма «Нанобиотехнологии», 2018-2020. ИПТМУ РАН-ИНЦ РАН.

Грант РФФИ: № 18-29-02060 мк, «Комбинированная термографическая и терагерцовая визуализация биологических тканей в диагностике новообразований кожи и слизистых», 2018-2020

Организация международных конференций

Международная Междисциплинарная Школа и Симпозиум для молодых ученых и студентов по оптике, лазерной физике и биофотонике (SFM) (председатель В.В. Тучин) (1996-2019).

Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine, SPIE, Photonics West, USA (co-chairs: James G. Fujimoto, Joseph A. Izatt, Valery V. Tuchin) (1997-2019)

Dynamics and Fluctuations in Biomedical Photonics, SPIE, Photonics West, USA (co-chairs: Valery V. Tuchin, Kirill V. Larin, Martin J. Leahy, Ruikang K. Wang) (2005-2019)

International Conference on Photonics and Imaging in Biology and Medicine (PIBM), China (chairs: Qingming Luo, Lihong V. Wang, Valery V. Tuchin) (2001-2017).